| 14388227 | Nelf-A | | | | | | Fly | | symbol | gene, null |
| 14388221 | NELF-B | | | | | | Fly | | symbol | gene, null |
| 14388228 | Nelf-E | | | | | | Fly | | symbol | gene, null |
| 1621569 | Nelfe | negative elongation factor complex member E, Rdbp | Enables chromatin binding activity. Involved in negative regulation of transcription elongation by RNA polymerase II. Is active in chromatin. Is expressed in brain and early conceptus. Orthologous to human NELFE (negative elongation factor complex member E). [pr ovided by Alliance of Genome Resources, Jul 2025] | 17 | 35069367 | 35075348 | Mouse | 125 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 619819 | Nsmf | NMDA receptor synaptonuclear signaling and neuronal migration factor | ENCODES a protein that exhibits calcium-dependent protein binding; INVOLVED IN cellular response to amino acid stimulus; cellular response to electrical stimulus; postsynapse to nucleus signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); Experimental Liver C irrhosis (ortholog); FOUND IN apical dendrite; cortical cytoskeleton; dendrite; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 3 | 28260018 | 28268790 | Rat | 165 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 733597 | NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] | 9 | 137447570 | 137459334 | Human | 198 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 733598 | Nsmf | NMDA receptor synaptonuclear signaling and neuronal migration factor | Predicted to enable calcium-dependent protein binding activity. Involved in cellular response to gonadotropin stimulus. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; liver; lung; and sensory organ. Human ortholog(s) of t his gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia and hypogonadotropic hypogonadism 9 with or without anosmia. Orthologous to human NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 24944370 | 24952893 | Mouse | 190 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12023116 | NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to electrical stimulus (ortholog); postsynapse to nucleus signaling pathway (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog) ; carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN apical dendrite (ortholog); cortical cytoskeleton (ortholog); dendrite (ortholog) | 9 | 108518698 | 108531316 | Bonobo | 48 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12216733 | NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); INVOLVED IN cellular response to amino acid stimulus (ortholog); cellular response to electrical stimulus (ortholog); postsynapse to nucleus signaling pathway (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog) ; carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN apical dendrite (ortholog); cortical cytoskeleton (ortholog); dendrite (ortholog) | 9 | 48287019 | 48295540 | Dog | 51 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1313651 | NELFA | negative elongation factor complex member A | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. T his gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008] | 4 | 1982723 | 2008974 | Human | 192 | symbol , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1313652 | Nelfa | negative elongation factor complex member A, Whsc2 | Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription elongation by RNA polymerase II. Located in nucleus. Is expressed in several structures, including blastocyst; early embryo; genitourinary system; liver; and spleen. Orthologous to human NELF font-weight:700;'>NELFA (negative elongation factor complex member A). [provided by Alliance of Genome Resources, Jul 2025] | 5 | 34055263 | 34093615 | Mouse | 114 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1317256 | Nelfb | negative elongation factor complex member B | This gene encodes subunit B of a metazoan-specific, four-subunit protein complex that regulates promoter-proximal pausing of RNA polymerase II. RNA polymerase II pausing is thought to be important for coordination of gene transcription during embryonic development and stress responses. Consistently, disruption of this gene in mouse causes inner cell mass deficiency and embryonic lethality. In addition, this gene is required for maintenance of mouse embryonic stem cells by preventing expression of developmental genes. In adult mice, conditional deletion of this gene results in cardiomyopathy and impaired response to cardiac stress. Multiple protein isoforms are encoded through the use of a non-AUG (CUG) initiation codon and an alternative downstream AUG initiation codon. In addition, alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] | 2 | 25089724 | 25101501 | Mouse | 87 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1603677 | NELFB | negative elongation factor complex member B | NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELF ;'>NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008] | 9 | 137255327 | 137273542 | Human | 82 | symbol , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1346942 | NELFCD | negative elongation factor complex member C/D | The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translat ion initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008] | 20 | 58981256 | 58995113 | Human | 74 | symbol , old_gene_name , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1623245 | Nelfcd | negative elongation factor complex member C/D, Th1l | Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NELF complex. Is expressed in several structures, including 1s t branchial arch; early embryo; limb; main olfactory bulb; and maxillary process. Orthologous to human NELFCD (negative elongation factor complex member C/D). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 174257623 | 174269298 | Mouse | 77 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 14010813 | NELFCD | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA binding (inferred); RNA polymerase inhibitor activity (inferred); translation elongation factor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcrip tion elongation by RNA polymerase II (inferred); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | | | | Pig | 27 | symbol , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1344973 | NELFE | negative elongation factor complex member E | The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008] | 6 | 31952087 | 31958971 | Human | 110 | symbol , COSMIC , description , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1590753 | Nelfcd | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); transcription pausing by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCI ATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; bisphenol A; tetrachloromethane | 3 | 183631968 | 183643088 | Rat | 78 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1305556 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding; molecular adaptor activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN positive regulation of protein modification process; positive regulation of transcription by RNA polymerase II; negative regulation of transcription elo ngation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 14 | 81033470 | 81057546 | Rat | 99 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8724917 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); molecular adaptor activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholo g); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | NW_004955514 | 1162993 | 1173278 | Chinchilla | 23 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 11997584 | NELFA | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATE S IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | 4 | 2119699 | 2147618 | Bonobo | 23 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12180648 | NELFA | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATE S IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | 3 | 62147948 | 62164039 | Dog | 24 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12546918 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATE S IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | NW_004936477 | 21442493 | 21459999 | Squirrel | 23 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 14052417 | NELFA | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATE S IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 25 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18739489 | NELFA | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATE S IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | | | | Green Monkey | 23 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18918177 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); molecular adaptor activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholo g); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252613 | nelfa | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625914966 | Nelfa | negative elongation factor complex member A | ENCODES a protein that exhibits chromatin binding (ortholog); molecular adaptor activity (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of protein modification process (ortholo g); positive regulation of transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 23 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 1307832 | Nelfb | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); negative regulation of stem cell differentiation (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polyme rase II transcription elongation pathway; FOUND IN cytoplasm (ortholog); NELF complex (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A | 3 | 28409045 | 28425564 | Rat | 85 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8768970 | Nelfb | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); negative regulation of stem cell differentiation (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polyme rase II transcription elongation pathway; FOUND IN cytoplasm (ortholog); NELF complex (ortholog); nucleoplasm (ortholog) | NW_004955513 | 5248190 | 5261018 | Chinchilla | 19 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 11862707 | NELFB | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (inferred); INVOLVED IN cell population proliferation (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of stem cell differentiation (inferred); PARTICIPATES IN RNA polymerase II transcript ion elongation pathway; FOUND IN cytoplasm (inferred); NELF complex (inferred); nucleoplasm (inferred) | 9 | 108314535 | 108333050 | Bonobo | 21 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12378040 | NELFB | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN transcription pausing by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | 9 | 48411725 | 48425044 | Dog | 20 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12471084 | Nelfb | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (inferred); INVOLVED IN cell population proliferation (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of stem cell differentiation (inferred); PARTICIPATES IN RNA polymerase II transcript ion elongation pathway; FOUND IN cytoplasm (inferred); NELF complex (inferred); nucleoplasm (inferred) | NW_004936669 | 726731 | 738714 | Squirrel | 21 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 13903315 | NELFB | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (inferred); INVOLVED IN cell population proliferation (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of stem cell differentiation (inferred); PARTICIPATES IN RNA polymerase II transcript ion elongation pathway; FOUND IN cytoplasm (inferred); NELF complex (inferred); nucleoplasm (inferred) | | | | Pig | 21 | symbol , description | gene, protein-coding, VALIDATED [RefSeq] |
| 18568913 | NELFB | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); negative regulation of stem cell differentiation (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polyme rase II transcription elongation pathway; FOUND IN cytoplasm (ortholog); NELF complex (ortholog); nucleoplasm (ortholog) | | | | Green Monkey | 19 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18907705 | Nelfb | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); negative regulation of stem cell differentiation (ortholog); stem cell differentiation (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; F OUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867287 | NELFB | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (inferred); INVOLVED IN cell population proliferation (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of stem cell differentiation (inferred); FOUND IN cytoplasm (inferred); NELF font-weight:700;'>NELF complex (inferred); nucleoplasm (inferred) | | | | Green Monkey | 14 | symbol , description | gene, protein-coding |
| 155249689 | nelfb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625979882 | Nelfb | negative elongation factor complex member B | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN cell population proliferation (ortholog); negative regulation of stem cell differentiation (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); PARTICIPATES IN RNA polyme rase II transcription elongation pathway; FOUND IN cytoplasm (ortholog); NELF complex (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 19 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 1303325 | Nelfe | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding; mRNA binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II; positive regulation of ERK1 and ERK2 cascade; positive regulation of protein modification process; PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN chromatin (ortholog); NELF complex (ortholog); nuclear body (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 20 | 3981259 | 3987016 | Rat | 118 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8797486 | Nelfe | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); mRNA binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK 1 and ERK2 cascade (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN chromatin (ortholog); NELF complex (ortholog); nuclear body (ortholog) | NW_004955437 | 467018 | 473084 | Chinchilla | 28 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 11980381 | NELFE | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RN A polymerase II transcription elongation pathway; FOUND IN chromatin (inferred); chromosome (inferred); NELF complex (inferred) | 6 | 31612924 | 31619732 | Bonobo | 35 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12215536 | NELFE | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RN A polymerase II transcription elongation pathway; FOUND IN chromatin (inferred); chromosome (inferred); NELF complex (inferred) | 12 | 1406411 | 1412387 | Dog | 35 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12664617 | Nelfe | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RN A polymerase II transcription elongation pathway; FOUND IN chromatin (inferred); chromosome (inferred); NELF complex (inferred) | NW_004936727 | 1589942 | 1596009 | Squirrel | 35 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 14201071 | NELFE | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RN A polymerase II transcription elongation pathway; FOUND IN chromatin (inferred); chromosome (inferred); NELF complex (inferred) | | | | Pig | 35 | symbol , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18584419 | NELFE | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RN A polymerase II transcription elongation pathway; FOUND IN chromatin (inferred); chromosome (inferred); NELF complex (inferred) | | | | Green Monkey | 35 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18923152 | Nelfe | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); mRNA binding (ortholog); RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); posi tive regulation of ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN chromatin (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | | | | Naked Mole-Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245282 | nelfe | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625925480 | Nelfe | negative elongation factor complex member E | ENCODES a protein that exhibits chromatin binding (ortholog); mRNA binding (ortholog); RNA binding (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transcription elongation by RNA polymerase II (ortholog); positive regulation of ERK 1 and ERK2 cascade (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; FOUND IN chromatin (ortholog); NELF complex (ortholog); nuclear body (ortholog) | | | | Black Rat | 28 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 8818196 | Nelfcd | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); transcription pausing by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCI ATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | NW_004955445 | 597826 | 610134 | Chinchilla | 18 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 11881777 | NELFCD | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA binding (inferred); RNA polymerase inhibitor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcription elongation by RNA polymerase II (inferred); PA RTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | 20 | 55332309 | 55346167 | Bonobo | 24 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12296173 | NELFCD | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA polymerase inhibitor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcription elongation by RNA polymerase II (inferred); PARTICIPATES IN RNA polyme rase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | 24 | 43685356 | 43743239 | Dog | 24 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 12699706 | Nelfcd | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA binding (inferred); RNA polymerase inhibitor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcription elongation by RNA polymerase II (inferred); PA RTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | NW_004936530 | 1474097 | 1481943 | Squirrel | 24 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18551696 | NELFCD | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA binding (inferred); RNA polymerase inhibitor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); negative regulation of transcription elongation by RNA polymerase II (inferred); PA RTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (inferred); nuclear body (inferred); nucleoplasm (inferred) | | | | Green Monkey | 24 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 18927502 | Nelfcd | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN transcription pausing by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCIATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN nuclear body (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253835 | nelfcd | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625882256 | Nelfcd | negative elongation factor complex member C/D | ENCODES a protein that exhibits RNA polymerase inhibitor activity (ortholog); INVOLVED IN negative regulation of transcription elongation by RNA polymerase II (ortholog); transcription pausing by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription elongation pathway; ASSOCI ATED WITH colon cancer (ortholog); colorectal cancer (ortholog); prostate cancer (ortholog); FOUND IN NELF complex (ortholog); nuclear body (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 18 | symbol , description | gene, protein-coding, MODEL [RefSeq] |
| 155257878 | nelfa.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405855929 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857158 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861502 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864203 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468133 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468414 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626469000 | nelfa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155255805 | nelfb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257005 | nelfe.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257472 | nelfe.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241888 | nelfcd.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1587010 | Nelfa-ps1 | negative elongation factor complex member A, pseudogene 1 | | 3 | 90929287 | 90932506 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 6498974 | Nelfe-ps1 | negative elongation factor complex member E, pseudogene 1 | | 9 | 61724018 | 61726397 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 40922093 | LOC119876763 | negative elongation factor E-like | ENCODES a protein that exhibits nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of DNA-templated transcription (inferred); FOUND IN chromosome (inferred); NELF complex (inferred); nucleus (i nferred) | | | | Dog | 9 | description | gene, protein-coding, MODEL [RefSeq] |
