Ndufs8 Gene Search Result

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13 records found for search term Ndufs8

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1309436	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); PARTICIPATES IN Alzheimer's disease ... (more) pathway; Huntington's disease pathway; oxidative phosphorylation pathway; ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 6-propyl-2-thiouracil	1	210569823	210573707	Rat	150	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
1319779	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8	This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the si ... (more) x to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq, Mar 2010]	11	68030681	68036644	Human	237	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1319780	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; and response to oxidative stress. Located in mit ... (more) ochondrion. Part of respiratory chain complex I. Is active in mitochondrial inner membrane. Is expressed in several structures, including early conceptus and oocyte. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 2. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8). [provided by Alliance of Genome Resources, Apr 2025]	19	3958863	3962774	Mouse	165	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8721742	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); ASSOCIATED WITH genetic disease (or ... (more) tholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog)	NW_004955422	17781374	17785395	Chinchilla	21	symbol	gene, protein-coding, MODEL [RefSeq]
12024724	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN aerobic respiration (inferred); mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I as ... (more) sembly (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)	11	63112536	63118600	Bonobo	33	symbol	gene, protein-coding, MODEL [RefSeq]
12360095	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); INVOLVED IN proton transmembrane transport (inferred); respiratory electron transport chain (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortho ... (more) log); FOUND IN mitochondrial inner membrane (ortholog)	18	49796558	49800805	Dog	26	symbol	gene, protein-coding, VALIDATED [RefSeq]
12717220	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN aerobic respiration (inferred); mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I as ... (more) sembly (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)	NW_004936599	2081493	2085635	Squirrel	32	symbol	gene, protein-coding, MODEL [RefSeq]
625835228	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (ortholog); mitochondrial respiratory chain complex I assembly (ortholog); ASSOCIATED WITH genetic disease (or ... (more) tholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog); respiratory chain complex I (ortholog)				Black Rat	21	symbol	gene, protein-coding, MODEL [RefSeq]
18921804	Ndufs8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits NADH dehydrogenase (ubiquinone) activity (ortholog); NADH dehydrogenase activity (ortholog); INVOLVED IN aerobic respiration (inferred); mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I assembly (inferred); ASS ... (more) OCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog); respiratory chain complex I (ortholog)				Naked Mole-Rat	30	symbol	gene, protein-coding, MODEL [RefSeq]
18755768	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN aerobic respiration (inferred); mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I as ... (more) sembly (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)				Green Monkey	33	symbol	gene, protein-coding, MODEL [RefSeq]
14297789	NDUFS8	NADH:ubiquinone oxidoreductase core subunit S8	ENCODES a protein that exhibits 4 iron, 4 sulfur cluster binding (inferred); iron-sulfur cluster binding (inferred); metal ion binding (inferred); INVOLVED IN mitochondrial electron transport, NADH to ubiquinone (inferred); mitochondrial respiratory chain complex I assembly (inferred); proton transm ... (more) embrane transport (inferred); ASSOCIATED WITH genetic disease (ortholog); Leigh disease (ortholog); mitochondrial complex I deficiency (ortholog); FOUND IN membrane (inferred); mitochondrial inner membrane (inferred); mitochondrion (inferred)				Pig	32	symbol	gene, protein-coding, MODEL [RefSeq]
155246716	ndufs8						Tropical Clawed Frog		symbol	gene, null
155249826	ndufs8.L						African Clawed Frog		symbol	gene, null