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19 records found for search term Myl2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
737270MYL2myosin light chain 2This gene encodes a major sarcomeric protein in mammalian striated muscle. The encoded protein plays a role in embryonic heart muscle structure and function, while phosphorylation of the encoded protein is involved in cardiac myosin cycling kinetics, torsion and function in adults. Mutations in this12110910845110921449Human874symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
737271Myl2myosin, light polypeptide 2, regulatory, cardiac, slowPredicted to enable actin monomer binding activity and calcium ion binding activity. Predicted to be a structural constituent of muscle. Involved in heart contraction; heart development; and positive regulation of the force of heart contraction. Acts upstream of or within several processes, includin5122230787122251536Mouse458symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1564245Myl2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (ortholog); calcium ion binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN cardiac muscle contraction; cell growth involved in cardiac muscle cell development; regulation of the force of heart contraction; PARTICIPATES I124011496440126236Rat185symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
8730005Myl2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (ortholog); calcium ion binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog);NW_00495548277084367713877Chinchilla60symbolgene, protein-coding, MODEL [RefSeq]
11832473MYL2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES I12108479941108489739Bonobo62symbolgene, protein-coding, MODEL [RefSeq]
12328700MYL2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES I2686241478632166Dog69symbolgene, protein-coding, PROVISIONAL [RefSeq]
12530356Myl2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES INW_00493655837462273753576Squirrel62symbolgene, protein-coding, MODEL [RefSeq]
18715381MYL2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES IGreen Monkey62symbolgene, protein-coding, MODEL [RefSeq]
155249025myl2Tropical Clawed Frogsymbolgene, null
626115509Myl2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (ortholog); calcium ion binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog);Black Rat48symbolgene, protein-coding, MODEL [RefSeq]
13866152MYL2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES IPig69symbolgene, protein-coding, PROVISIONAL [RefSeq]
18913341Myl2myosin light chain 2ENCODES a protein that exhibits actin monomer binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN cardiac muscle contraction (ortholog); cardiac myofibril assembly (ortholog); cell growth involved in cardiac muscle cell development (ortholog); PARTICIPATES INaked Mole-Rat62symbolgene, protein-coding, MODEL [RefSeq]
155243854myl2.LAfrican Clawed Frogsymbolgene, null
155258159myl2.SAfrican Clawed Frogsymbolgene, null
3141Myl11myosin light chain 11ENCODES a protein that exhibits structural constituent of muscle (ortholog); INVOLVED IN immune response; skeletal muscle tissue development; muscle contraction (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); distal arthrogryposis (ortholog); distal arthrogryposis type 1C (ortholog); FO1191257432191263046Rat77old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1606574MYL12Amyosin light chain 12AThis gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing trans1832474823256237Human106old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1317934MYL7myosin light chain 7Predicted to enable calcium ion binding activity. Predicted to be involved in cardiac muscle tissue development and heart contraction. Located in A band. [provided by Alliance of Genome Resources, Jul 2025]74413886444141332Human106old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1317935Myl7myosin, light polypeptide 7, regulatoryPredicted to enable calcium ion binding activity. Predicted to be involved in cardiac muscle tissue development and heart contraction. Located in dendritic spine. Is expressed in several structures, including gastrocnemius muscle; heart; liver; uterus; and vascular system. Orthologous to human MYL7 1158466375848782Mouse127old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1604762MYLK3myosin light chain kinase 3Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[suppl164670228246763246Human114descriptiongene, protein-coding, VALIDATED [RefSeq]