| 62001 | Muc5ac | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus; cellular response to glucocorticoid stimulus; cellular response to retinoic acid; ASSOCIATED WITH allergic rhinitis; asthma; chronic obstructive pulmonary disease; FOUND IN extracellular space; mucus layer (ortholog); INTERACTS WITH (E)-roxithromycin; (R,R,R)-alpha-tocopherol; 1,8-cineole | 1 | 206293717 | 206326006 | Rat | 263 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 62293 | Muc5ac | mucin 5, subtypes A and C, tracheobronchial/gastric | Acts upstream of or within maintenance of lens transparency. Located in extracellular space. Is expressed in male reproductive gland or organ; nasal cavity epithelium; respiratory system; and stomach. Used to study dry eye syndrome. Human ortholog(s) of this gene implicated in chronic obstructive pu lmonary disease and dry eye syndrome. Orthologous to human MUC5AC (mucin 5AC, oligomeric mucus/gel-forming). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 141342695 | 141372964 | Mouse | 277 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 737024 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | Predicted to enable extracellular matrix constituent, lubricant activity. Predicted to be an extracellular matrix structural constituent. Predicted to act upstream of or within maintenance of lens transparency. Located in extracellular space and mucus layer. Implicated in dry eye syndrome. Biomarker of several diseases, including Sjogren's syndrome; biliary tract disease (multiple); cystic fibrosis; eye disease (multiple); and pancreatic cancer (multiple). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 1157953 | 1201138 | Human | 291 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8793705 | Muc5ac | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | NW_004955476 | 11061405 | 11084294 | Chinchilla | 73 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11814707 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | 11 | 1191223 | 1234373 | Bonobo | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12218892 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | 18 | 45471232 | 45498961 | Dog | 73 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12455607 | Muc5ac | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog) | NW_004936816 | 129926 | 159396 | Squirrel | 75 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14269151 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | | | | Pig | 77 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626008058 | Muc5ac | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | | | | Black Rat | 73 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13887574 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | | | | | Pig | | symbol | gene, protein-coding |
| 18777349 | MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog); mucus layer (ortholog) | | | | Green Monkey | 73 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907319 | Muc5ac | mucin 5AC, oligomeric mucus/gel-forming | INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to glucocorticoid stimulus (ortholog); cellular response to retinoic acid (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); angle-closure glaucoma (ortholog); asthma (ortholog); FOUND IN extracell ular space (ortholog) | | | | Naked Mole-Rat | 74 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 598151636 | muc5ac | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 628359054 | muc5ac.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626176338 | muc5ac.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329056 | muc5acl | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 329329057 | muc5acl.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329302 | muc5acl.S | | | | | | African Clawed Frog | | symbol | gene, null |