| 1305198 | Meis2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN pancreas development; response to growth factor; response to mech anical stimulus; ASSOCIATED WITH brain infarction; Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 3 | 123197066 | 123399002 | Rat | 188 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1313085 | MEIS2 | Meis homeobox 2 | This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008] | 15 | 36889204 | 37101311 | Human | 263 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1550144 | Meis2 | Meis homeobox 2 | This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcriptional regulators and several members have been shown to be essential contributors to developmental programs. In mice, a knock-out of this gene leads to lethality at embryonic day 14, accompanied with hemorrhaging. Embryos lacking this gene show defects in tissues derived from the neural crest, suggesting a critical role of this gene during cranial and cardiac neural crest cell development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] | 2 | 115691745 | 115897925 | Mouse | 237 | symbol , old_gene_name , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8829673 | Meis2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); negative regulation of myeloid cell d ifferentiation (ortholog); pancreas development (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (ortholog) | NW_004955416 | 4104114 | 4311791 | Chinchilla | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11670863 | MEIS2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); resp onse to growth factor (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred) | 15 | 15814739 | 16025512 | Bonobo | 39 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12268396 | MEIS2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); resp onse to growth factor (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred) | 30 | 4422451 | 4627277 | Dog | 48 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12479121 | Meis2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); resp onse to growth factor (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred) | NW_004936471 | 800510 | 1006054 | Squirrel | 41 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 13968197 | MEIS2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); resp onse to growth factor (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH deoxynivalenol; graphene oxide | | | | Pig | 50 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155258013 | meis2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18919665 | Meis2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); negative regulation of myeloid cell differentiation (ortholog); pancreas development (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 42 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625836128 | Meis2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN eye development (ortholog); negative regulation of myeloid cell d ifferentiation (ortholog); pancreas development (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18639396 | MEIS2 | Meis homeobox 2 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); resp onse to growth factor (ortholog); ASSOCIATED WITH brain infarction (ortholog); Calcification of Aortic Valve (ortholog); cleft palate (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 39 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 20866326 | MEIS2 | Meis homeobox 2 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155239322 | meis2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626188956 | meis2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 18902573 | LOC110346459 | homeobox protein Meis2-like | | | | | Naked Mole-Rat | | name | gene, pseudo, MODEL [RefSeq] |
| 8857758 | LOC102015923 | homeobox protein Meis2 pseudogene | | NW_004955407 | 24891666 | 24892871 | Chinchilla | | name | gene, pseudo, MODEL [RefSeq] |
| 16562224 | AC078909.1 | novel transcript, antisense to MEIS2 | | | | | Human | | name | gene, lncrna |
| 18936157 | Meis1 | Meis homeobox 1 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN angiogenesis (ortholog); blood vessel morphogenesis (orthol og); cell growth involved in cardiac muscle cell development (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cardiomegaly (ortholog); heart disease (ortholog); FOUND IN nucleoplasm (ortholog); transcription regulator complex (ortholog) | | | | Naked Mole-Rat | 45 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 1590611 | Pknox2 | PBX/knotted 1 homeobox 2 | ENCODES a protein that exhibits actin filament binding (ortholog); actin monomer binding (ortholog); DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH alcohol dependence (ortholog); Familial Prostate Cancer (ortholog); FOUND IN actin cyt oskeleton (ortholog); cytoplasm (ortholog); microtubule cytoskeleton (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 8 | 44789464 | 45051933 | Rat | 118 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |