MEIS2 (Meis homeobox 2) - Rat Genome Database

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Gene: MEIS2 (Meis homeobox 2) Pan paniscus
Analyze
Symbol: MEIS2
Name: Meis homeobox 2
RGD ID: 11670863
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); RNA polymerase II cis-regulatory region sequence-specific DNA binding (inferred); INVOLVED IN eye development (ortholog); pancreas development (ortholog); response to growth factor (ortholog); ASSOCIATED WITH Bloom syndrome (ortholog); brain infarction (ortholog); Calcification of Aortic Valve (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: homeobox protein Meis2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21626,114,262 - 26,324,918 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11530,268,369 - 30,478,883 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01515,814,739 - 16,025,512 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11534,072,665 - 34,283,411 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1534,072,665 - 34,282,477 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MEIS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21626,114,262 - 26,324,918 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11530,268,369 - 30,478,883 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01515,814,739 - 16,025,512 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11534,072,665 - 34,283,411 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1534,072,665 - 34,282,477 (-)Ensemblpanpan1.1panPan2
MEIS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381536,889,204 - 37,101,311 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1536,889,204 - 37,101,299 (-)EnsemblGRCh38hg38GRCh38
GRCh371537,181,405 - 37,393,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361534,970,524 - 35,180,792 (-)NCBINCBI36Build 36hg18NCBI36
Celera1513,943,263 - 14,153,527 (-)NCBICelera
Cytogenetic Map15q14NCBI
HuRef1514,029,111 - 14,239,280 (-)NCBIHuRef
CHM1_11537,301,775 - 37,511,985 (-)NCBICHM1_1
T2T-CHM13v2.01534,694,657 - 34,906,720 (-)NCBIT2T-CHM13v2.0
Meis2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392115,691,745 - 115,897,925 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2115,693,545 - 115,896,320 (-)EnsemblGRCm39 Ensembl
GRCm382115,861,264 - 116,067,537 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2115,863,064 - 116,065,839 (-)EnsemblGRCm38mm10GRCm38
MGSCv372115,687,000 - 115,890,794 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362115,554,510 - 115,756,553 (-)NCBIMGSCv36mm8
Celera2117,003,666 - 117,210,747 (-)NCBICelera
Cytogenetic Map2E4- E5NCBI
cM Map258.28NCBI
Meis2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83123,197,066 - 123,399,002 (-)NCBIGRCr8
mRatBN7.23102,742,904 - 102,944,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3102,742,900 - 102,949,696 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3106,398,249 - 106,600,359 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03114,997,287 - 115,199,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03112,659,875 - 112,860,693 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03107,560,172 - 107,762,732 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3107,559,997 - 107,760,589 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03114,124,722 - 114,327,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43101,915,966 - 102,117,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13101,812,373 - 102,015,498 (-)NCBI
Celera3101,688,008 - 101,887,707 (-)NCBICelera
Cytogenetic Map3q35NCBI
Meis2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554164,101,977 - 4,311,791 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554164,104,114 - 4,311,791 (-)NCBIChiLan1.0ChiLan1.0
MEIS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1304,422,451 - 4,627,277 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl304,422,440 - 4,741,335 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha304,476,676 - 4,681,235 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0304,544,212 - 4,749,027 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl304,544,217 - 4,749,667 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1304,471,642 - 4,676,294 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0304,569,335 - 4,774,290 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0304,703,783 - 4,908,705 (-)NCBIUU_Cfam_GSD_1.0
Meis2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864082,952,452 - 83,157,991 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936471798,739 - 1,006,047 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936471800,510 - 1,006,054 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEIS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1134,013,820 - 134,223,012 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11134,013,642 - 134,223,013 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21149,911,450 - 149,974,264 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MEIS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12645,844,214 - 46,054,325 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604894,869,693 - 95,081,805 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Meis2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248044,210,770 - 4,413,261 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248044,210,765 - 4,413,284 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000029143   ⟹   ENSPPAP00000007095
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1534,072,665 - 34,282,477 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029147   ⟹   ENSPPAP00000007099
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1534,076,612 - 34,280,844 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000029154   ⟹   ENSPPAP00000007104
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1534,277,507 - 34,281,401 (-)Ensembl
RefSeq Acc Id: XM_003816705   ⟹   XP_003816753
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,115,637 - 26,324,918 (-)NCBI
NHGRI_mPanPan11530,269,655 - 30,477,659 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,024,761 (-)NCBI
PanPan1.11534,072,665 - 34,282,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003816706   ⟹   XP_003816754
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,115,637 - 26,324,918 (-)NCBI
NHGRI_mPanPan11530,269,655 - 30,477,659 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,024,761 (-)NCBI
PanPan1.11534,072,665 - 34,282,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003816707   ⟹   XP_003816755
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,114,262 - 26,324,918 (-)NCBI
NHGRI_mPanPan11530,268,369 - 30,477,659 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,024,761 (-)NCBI
PanPan1.11534,072,665 - 34,282,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003816708   ⟹   XP_003816756
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,114,262 - 26,324,918 (-)NCBI
NHGRI_mPanPan11530,268,369 - 30,477,659 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,024,761 (-)NCBI
PanPan1.11534,072,665 - 34,282,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008969808   ⟹   XP_008968056
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,114,262 - 26,323,093 (-)NCBI
NHGRI_mPanPan11530,268,369 - 30,476,914 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,023,249 (-)NCBI
PanPan1.11534,072,670 - 34,281,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008969810   ⟹   XP_008968058
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,115,637 - 26,323,093 (-)NCBI
NHGRI_mPanPan11530,269,655 - 30,476,914 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,023,249 (-)NCBI
PanPan1.11534,072,665 - 34,281,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008969811   ⟹   XP_008968059
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,115,637 - 26,323,093 (-)NCBI
NHGRI_mPanPan11530,269,655 - 30,476,914 (-)NCBI
Mhudiblu_PPA_v01515,816,033 - 16,023,249 (-)NCBI
PanPan1.11534,072,670 - 34,281,379 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034938502   ⟹   XP_034794393
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,114,262 - 26,321,886 (-)NCBI
NHGRI_mPanPan11530,268,369 - 30,475,976 (-)NCBI
Mhudiblu_PPA_v01515,814,739 - 16,022,334 (-)NCBI
RefSeq Acc Id: XM_063596534   ⟹   XP_063452604
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21626,114,262 - 26,321,886 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_003816755   ⟸   XM_003816707
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003816754   ⟸   XM_003816706
- Peptide Label: isoform X6
- UniProtKB: A0A2R8ZW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816756   ⟸   XM_003816708
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZQ82 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003816753   ⟸   XM_003816705
- Peptide Label: isoform X4
- UniProtKB: A0A2R8ZW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008968058   ⟸   XM_008969810
- Peptide Label: isoform X5
- UniProtKB: A0A2R8ZW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008968059   ⟸   XM_008969811
- Peptide Label: isoform X7
- UniProtKB: A0A2R8ZW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008968056   ⟸   XM_008969808
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_034794393   ⟸   XM_034938502
- Peptide Label: isoform X8
RefSeq Acc Id: ENSPPAP00000007104   ⟸   ENSPPAT00000029154
RefSeq Acc Id: ENSPPAP00000007099   ⟸   ENSPPAT00000029147
RefSeq Acc Id: ENSPPAP00000007095   ⟸   ENSPPAT00000029143
RefSeq Acc Id: XP_063452604   ⟸   XM_063596534
- Peptide Label: isoform X9
Protein Domains
Homeobox


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000026165 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000029143.1 UniProtKB/TrEMBL
  ENSPPAT00000029147.1 UniProtKB/TrEMBL
  ENSPPAT00000029154.1 UniProtKB/TrEMBL
Gene3D-CATH Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Homeobox_KN_domain UniProtKB/TrEMBL
  PKNOX/Meis_N UniProtKB/TrEMBL
NCBI Gene MEIS2 ENTREZGENE
PANTHER HOMEOBOX PROTEIN MEIS2 UniProtKB/TrEMBL
  HOMEOBOX PROTEIN TRANSCRIPTION FACTORS UniProtKB/TrEMBL
Pfam Homeobox_KN UniProtKB/TrEMBL
  Meis_PKNOX_N UniProtKB/TrEMBL
PROSITE HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt A0A2R8ZQ82 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZW29 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8ZW34_PANPA UniProtKB/TrEMBL