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Pathways
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44 records found for search term Mbd3
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1307389Mbd3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (ortholog); methyl-CpG binding (ortholog); INVOLVED IN embryonic organ development; epigenetic regulation of gene expression; response to bisphenol A; PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATED WITH Experimental Seizures; 799610539970845Rat138symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1316562MBD3methyl-CpG binding domain protein 3DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multis1915735961592865Human150symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1316563Mbd3methyl-CpG binding domain protein 3This gene encodes a member of the MBD family of nuclear proteins that contain a methyl-CpG binding domain (MBD). The encoded protein is a component of the nucleosome remodeling and histone deacetylation (NuRD) complex. Deletion of this gene causes embryonic lethality in mice. Embryonic stem cells la108022837380235365Mouse150symbol , old_gene_name , PhenoGengene, protein-coding, REVIEWED [RefSeq]
8929451Mbd3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (ortholog); methyl-CpG binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATENW_00495549563854496388911Chinchilla34symbolgene, protein-coding, MODEL [RefSeq]
11851868MBD3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;Bonobo42symbolgene, protein-coding, MODEL [RefSeq]
12233422MBD3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;205729671357312988Dog46symbolgene, protein-coding, MODEL [RefSeq]
12539558Mbd3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;NW_004936588865046873821Squirrel44symbolgene, protein-coding, MODEL [RefSeq]
14231145MBD3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;Pig46symbolgene, protein-coding, MODEL [RefSeq]
18743623MBD3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;Green Monkey44symbolgene, protein-coding, MODEL [RefSeq]
18911165Mbd3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (inferred); methyl-CpG binding (inferred); INVOLVED IN embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); in utero embryonic development (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway;Naked Mole-Rat45symbolgene, protein-coding, MODEL [RefSeq]
155241829mbd3Tropical Clawed Frogsymbolgene, null
626162452Mbd3methyl-CpG binding domain protein 3ENCODES a protein that exhibits DNA binding (ortholog); methyl-CpG binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); embryonic organ development (ortholog); epigenetic regulation of gene expression (ortholog); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; ASSOCIATEBlack Rat34symbolgene, protein-coding, MODEL [RefSeq]
405858487mbd3.LAfrican Clawed Frogsymbolgene, null
405858982mbd3.LAfrican Clawed Frogsymbolgene, null
405863061mbd3.LAfrican Clawed Frogsymbolgene, null
405863739mbd3.LAfrican Clawed Frogsymbolgene, null
626468680mbd3.LAfrican Clawed Frogsymbolgene, null
155241828mbd3.SAfrican Clawed Frogsymbolgene, null
1313538DPEP3dipeptidase 3This gene encodes a membrane-bound glycoprotein from the family of dipeptidases involved in hydrolytic metabolism of various dipeptides, including penem and carbapenem beta-lactam antibiotics. This gene is located on chromosome 16 in a cluster with another member of this family. Alternatively splice166797566367980499Human45old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1317931Mbd3l1methyl-CpG binding domain protein 3-like 1Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MBD391838965518396594Mouse22symbol , old_gene_name , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
16564420AC005943.1novel transcript, readthrough between UQCR11 and MBD3Humannamegene, protein-coding
5477527MBD3L3methyl-CpG binding domain protein 3 like 3Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]1970562077058676Human11symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
5477533MBD3L4methyl-CpG binding domain protein 3 like 4This gene encodes a member of a family of proteins that are related to methyl-CpG-binding proteins but lack the methyl-CpG binding domain. There is no definitive support for transcription of this locus, and the transcript structure is inferred from other family members. [provided by RefSeq, Aug 20091970377497040179Human9symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, INFERRED [RefSeq]
5477562MBD3L5methyl-CpG binding domain protein 3 like 5Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]1970305787033011Human8symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1317930MBD3L1methyl-CpG binding domain protein 3 like 1This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein is localized to discrete areas in the nucleus, and expression appears to be restricted to round spermatids, suggesting that the protein plays a role in the postmeiotic stag1988323778843319Human19symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
1601828MBD3L2methyl-CpG binding domain protein 3 like 2This gene encodes a protein that is related to methyl-CpG-binding proteins but lacks the methyl-CpG binding domain. The protein has been found in germ cell tumors and some somatic tissues. [provided by RefSeq, Jul 2008]1970493217051735Human26symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1308259Mbd3l1methyl-CpG binding domain protein 3-like 1FOUND IN nucleus (inferred); INTERACTS WITH atrazine; bisphenol A; arsane (ortholog)82442686524436687Rat15symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8754788Mbd3l1methyl-CpG binding domain protein 3 like 1NW_004955563584541588597Chinchilla3symbolgene, protein-coding, MODEL [RefSeq]
11830292MBD3L1methyl-CpG binding domain protein 3 like 1FOUND IN nucleus (inferred)1984071468411314Bonobo4symbolgene, protein-coding, MODEL [RefSeq]
12069770MBD3L1methyl-CpG binding domain protein 3 like 1FOUND IN nucleus (inferred)205187672951880970Dog8symbolgene, protein-coding, MODEL [RefSeq]
12666795Mbd3l1methyl-CpG binding domain protein 3 like 1NW_00493658855037225504297Squirrel3symbolgene, protein-coding, MODEL [RefSeq]
18562810MBD3L1methyl-CpG binding domain protein 3 like 1FOUND IN nucleus (inferred)Green Monkey4symbolgene, protein-coding, MODEL [RefSeq]
18927032Mbd3l1methyl-CpG binding domain protein 3 like 1FOUND IN nucleus (inferred)Naked Mole-Rat4symbolgene, protein-coding, MODEL [RefSeq]
626125848Mbd3l1methyl-CpG binding domain protein 3 like 1Black Rat3symbolgene, protein-coding, MODEL [RefSeq]
1308833Mbd3l2methyl-CpG binding domain protein 3-like 2INVOLVED IN regulation of chromatin organization (ortholog); regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Stomach Neoplasms (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH bisphenol A; vinclozolin; 2,3',4,4',5-Pentachlorobiphenyl (ortholog)82388380923890378Rat25symbol , PhenoGen , old_gene_symbolgene, pseudo, INFERRED [RefSeq]
1318832Mbd3l2methyl-CpG binding domain protein 3-like 2Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MBD391834191118357612Mouse29symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
41015846Mbd3l3methyl-CpG binding domain protein 3 like 3FOUND IN nucleus (inferred)82427630124277672Rat1symbol , PhenoGengene, protein-coding, MODEL [RefSeq]
12859063MBD3L2Bmethyl-CpG binding domain protein 3 like 2BPredicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]1970189697021431Human5symbol , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1596100Mbd3l2-ps1methyl-CpG binding domain protein 3-like 2, pseudogene 182437718524378712Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
18915425LOC101703117putative methyl-CpG-binding domain protein 3-like 5FOUND IN nucleus (inferred)Naked Mole-Rat1old_gene_symbolgene, protein-coding, MODEL [RefSeq]
14174637LOC102159280methyl-CpG-binding domain protein 3-like 1Pigold_gene_symbolgene, protein-coding, MODEL [RefSeq]
1312368MBD2methyl-CpG binding domain protein 2DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding d185415160654224669Human190descriptiongene, protein-coding, REVIEWED [RefSeq]
1349232MECP2methyl-CpG binding protein 2DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding dX154021573154097717Human1723descriptiongene, protein-coding, REVIEWED [RefSeq]
16565176AC008734.2novel transcript, sense intronic to MBD3L1Humannamegene, lncrna