| 1558594 | Lbx1 | ladybird homeobox 1 | Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including heart looping; negative regulation of glutamatergic neuron differentiation; and neuron differentiation. Part of transcription regulator complex. Is expressed in several structures, including ce ntral nervous system; embryo mesenchyme; heart; skeletal musculature; and urinary system. Human ortholog(s) of this gene implicated in congenital central hypoventilation syndrome. Orthologous to human LBX1 (ladybird homeobox 1). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 45221123 | 45225280 | Mouse | 103 | symbol , old_gene_name , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1564197 | Lbx1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenit al Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN transcription regulator complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; paracetamol | 1 | 254033009 | 254034826 | Rat | 51 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1606568 | LBX1 | ladybird homeobox 1 | This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by Re fSeq, Jul 2008] | 10 | 101226994 | 101229463 | Human | 127 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8800992 | Lbx1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenit al Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN transcription regulator complex (ortholog) | NW_004955485 | 9003329 | 9005987 | Chinchilla | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12380641 | LBX1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negat ive regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenital Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred) | 28 | 13872846 | 13875521 | Dog | 31 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12644986 | Lbx1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negat ive regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenital Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred) | NW_004936600 | 4505280 | 4507934 | Squirrel | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 32727903 | LBX1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenit al Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN transcription regulator complex (ortholog) | 10 | 97830026 | 97832751 | Bonobo | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626040605 | Lbx1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenit al Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN transcription regulator complex (ortholog) | | | | Black Rat | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155232454 | lbx1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14092336 | LBX1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negat ive regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenital Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred) | | | | Pig | 31 | symbol , old_gene_name | gene, protein-coding, INFERRED [RefSeq] |
| 18454888 | LBX1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negat ive regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenital Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN nucleus (inferred); transcription regulator complex (inferred) | | | | Green Monkey | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18918913 | Lbx1 | ladybird homeobox 1 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); INVOLVED IN heart looping (ortholog); negative regulation of cell population proliferation (ortholog); negative regulation of neuron differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Congenit al Central Hypoventilation Syndrome 3 (ortholog); Desbuquois dysplasia (ortholog); FOUND IN transcription regulator complex (ortholog) | | | | Naked Mole-Rat | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155244479 | lbx1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244268 | lbx1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7245672 | LBX1-AS1 | LBX1 antisense RNA 1 | INTERACTS WITH aflatoxin B1; benzo[a]pyrene; bis(2-ethylhexyl) phthalate | 10 | 101229594 | 101238859 | Human | 4 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1553205 | Skor1 | SKI family transcriptional corepressor 1 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Par t of transcription regulator complex. Is expressed in bladder; central nervous system; dorsal root ganglion; and lung. Orthologous to human SKOR1 (SKI family transcriptional corepressor 1). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 63045446 | 63056243 | Mouse | 59 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1605497 | SKOR1 | SKI family transcriptional corepressor 1 | Enables SMAD binding activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of BMP signaling pathway. Located in dendrite and neuronal cell body. [provided by Alliance of Genome Resources, Jul 2025] | 15 | 67825509 | 67834582 | Human | 54 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1619466 | Skor2 | SKI family transcriptional corepressor 2 | Enables SMAD binding activity; chromatin binding activity; and histone deacetylase binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including cerebellar Purkinje cell differentiation; regulation of neural precursor cell proliferation; and regulation of signal transduction. Located in nucleus. Is expressed in brain; dorsal root ganglion; and spinal cord. Orthologous to human SKOR2 (SKI family transcriptional corepressor 2). [provided by Alliance of Genome Resources, Jul 2025] | 18 | 76934428 | 76988759 | Mouse | 69 | old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 3160638 | SKOR2 | SKI family transcriptional corepressor 2 | Enables SMAD binding activity and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 18 | 47206169 | 47251660 | Human | 43 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |