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Pathways
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19 records found for search term Lat2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
631397Lat2linker for activation of T cells family, member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN B cell activation (ortholog); B cell receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental Leukemia122774064727754760Rat124symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
1342914LAT2linker for activation of T cells family member 2This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. [provided by RefSeq, Jul 2008]77421000674229834Human121symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1617564Lat2linker for activation of T cells family, member 2Predicted to enable SH2 domain binding activity. Predicted to be involved in B cell activation; B cell receptor signaling pathway; and calcium-mediated signaling. Predicted to be located in membrane raft. Predicted to be active in plasma membrane. Is expressed in several structures, including genito5134628957134648637Mouse156symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9062988Lat2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN B cell activation (ortholog); B cell receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaNW_0049554561367419013688611Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
12125951LAT2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental Leukemia (ortholog); FOUND IN membrane raft (ortholog); plasma membrane (orth661609396175271Dog16symbolgene, protein-coding, MODEL [RefSeq]
12561473Lat2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN B cell activation (ortholog); B cell receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaNW_00493654332509563262668Squirrel13symbolgene, protein-coding, MODEL [RefSeq]
18453790LAT2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (inferred); INVOLVED IN B cell activation (inferred); B cell receptor signaling pathway (inferred); calcium-mediated signaling (inferred); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaGreen Monkey18symbolgene, protein-coding, MODEL [RefSeq]
626037882Lat2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN B cell activation (ortholog); B cell receptor signaling pathway (ortholog); calcium-mediated signaling (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaBlack Rat13symbolgene, protein-coding, MODEL [RefSeq]
11916450LAT2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (inferred); INVOLVED IN B cell activation (inferred); B cell receptor signaling pathway (inferred); calcium-mediated signaling (inferred); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaBonobo18symbolgene, protein-coding, MODEL [RefSeq]
14200231LAT2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (inferred); INVOLVED IN B cell activation (inferred); B cell receptor signaling pathway (inferred); calcium-mediated signaling (inferred); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental LeukemiaPig14symbolgene, protein-coding, VALIDATED [RefSeq]
18912417Lat2linker for activation of T cells family member 2ENCODES a protein that exhibits SH2 domain binding (ortholog); INVOLVED IN intracellular signal transduction (ortholog); ASSOCIATED WITH acute promyelocytic leukemia (ortholog); Disease Progression (ortholog); Experimental Leukemia (ortholog); FOUND IN membrane raft (ortholog)Naked Mole-Rat15symbolgene, protein-coding, MODEL [RefSeq]
619904Slc7a8solute carrier family 7 member 8ENCODES a protein that exhibits amino acid transmembrane transporter activity (ortholog); antiporter activity (ortholog); glycine transmembrane transporter activity (ortholog); INVOLVED IN amino acid import across plasma membrane (ortholog); amino acid transport (ortholog); glycine transport (orthol153215301632212715Rat252old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
733687Slc7a8solute carrier family 7 (cationic amino acid transporter, y+ system), member 8Enables L-amino acid transmembrane transporter activity; glycine transmembrane transporter activity; and thyroid hormone transmembrane transporter activity. Involved in carboxylic acid transport and thyroid hormone transport. Acts upstream of or within L-amino acid transport. Located in apical plasm145495967255019343Mouse262old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1345085SLC7A8solute carrier family 7 member 8Enables several functions, including neutral L-amino acid transmembrane transporter activity; protein heterodimerization activity; and secondary active transmembrane transporter activity. Involved in L-alanine import across plasma membrane; L-leucine import across plasma membrane; and thyroid hormon142312529523183660Human250old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
12386357SLC7A8solute carrier family 7 member 8ENCODES a protein that exhibits amino acid transmembrane transporter activity (inferred); antiporter activity (inferred); glycine transmembrane transporter activity (inferred); INVOLVED IN L-amino acid transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide phar834302083479985Dog69old_gene_symbolgene, protein-coding, INFERRED [RefSeq]
14123156SLC7A8solute carrier family 7 member 8ENCODES a protein that exhibits amino acid transmembrane transporter activity (inferred); antiporter activity (inferred); glycine transmembrane transporter activity (inferred); INVOLVED IN L-amino acid transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharPig71old_gene_symbolgene, protein-coding, MODEL [RefSeq]
1309193Slc7a6solute carrier family 7 member 6ENCODES a protein that exhibits arginine binding (ortholog); basic amino acid transmembrane transporter activity (ortholog); L-arginine transmembrane transporter activity (ortholog); INVOLVED IN L-arginine transmembrane transport; nitric oxide biosynthetic process; amino acid import across plasma me195098245951010140Rat159old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1319397SLC7A6solute carrier family 7 member 6Enables L-lysine:L-arginine antiporter activity and arginine binding activity. Involved in L-arginine transmembrane transport; L-leucine transport; and ornithine transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]166826452668301819Human153old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1553153Slc7a6solute carrier family 7 (cationic amino acid transporter, y+ system), member 6Predicted to enable L-lysine:L-arginine antiporter activity and arginine binding activity. Involved in glycine betaine transport. Predicted to be located in plasma membrane. Is expressed in brain; cumulus oophorus; embryo; gonad; and oocyte. Orthologous to human SLC7A6 (solute carrier family 7 membe8106894718106925346Mouse160old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]