| 1309204 | Klf12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol | 15 | 83037548 | 83469998 | Rat | 160 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319416 | KLF12 | KLF transcription factor 12 | Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expressi on of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 13 | 73686089 | 74306045 | Human | 159 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1616852 | Klf12 | Kruppel-like transcription factor 12 | Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of tran scription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human KLF12 (KLF transcription factor 12). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 100103617 | 100719681 | Mouse | 172 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8701952 | Klf12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog) | NW_004955404 | 32715636 | 33127525 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11728648 | KLF12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred) | 13 | 54916443 | 55535131 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12217374 | KLF12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred) | 22 | 27695017 | 28264813 | Dog | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12644460 | Klf12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of tra nscription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred) | NW_004936511 | 6992131 | 7292484 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14020565 | KLF12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 23 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18431474 | KLF12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910281 | Klf12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of tr anscription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867380 | KLF12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription repressor activity, RNA polymerase II-specific (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (inferred) | | | | Green Monkey | 7 | symbol | gene, protein-coding |
| 155234911 | klf12 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625926085 | Klf12 | KLF transcription factor 12 | ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH schizophrenia (ortholog); substance-related disorder (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242082 | klf12.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155235401 | klf12.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16569153 | AL159972.1 | novel transcript, sense intronic to KLF12 | | | | | Human | | name | gene, lncrna |
