| 1306646 | Klf11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to endothelin; negative regulation of cell p opulation proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acrylamide | 6 | 47014312 | 47026152 | Rat | 168 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605424 | KLF11 | KLF transcription factor 11 | The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010] | 2 | 10043550 | 10054836 | Human | 223 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1616592 | Klf11 | Kruppel-like transcription factor 11 | Enables DNA-binding transcription factor activity. Involved in negative regulation of DNA-templated transcription. Predicted to be located in cytosol; focal adhesion; and nuclear body. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; liver; and sensory organ. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 7 and type 2 diabetes mellitus. Orthologous to human KLF11 (KLF transcription factor 11). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 24701370 | 24712781 | Mouse | 184 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8927099 | Klf11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to endothelin (ortholog); negative regulatio n of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004955487 | 5448869 | 5454322 | Chinchilla | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11763879 | KLF11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to endothelin (ortholog); negative regulation of cell population proliferation (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 2A | 10027152 | 10051445 | Bonobo | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12423065 | KLF11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to endothelin (ortholog); negative regulation of cell population proliferation (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | 17 | 7038282 | 7049880 | Dog | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12652855 | Klf11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to endothelin (ortholog); negative regulatio n of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004936532 | 6282313 | 6290569 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18768289 | KLF11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); INVOLVED IN cellular response to endothelin (ortholog); negative regulation of cell population proliferation (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13958158 | KLF11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN cellular response to endothelin (ortholog); negative regulation of cell population prolife ration (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 33 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 626069923 | Klf11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to endothelin (ortholog); negative regulatio n of cell population proliferation (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Black Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18911849 | Klf11 | KLF transcription factor 11 | ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); sequence-specific double-stranded DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to endothelin (ortholog); negative regulation of cell population proli feration (ortholog); negative regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH diabetes mellitus (ortholog); Hepatomegaly (ortholog); Insulin Resistance (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238267 | klf11 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155250692 | klf11.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155245552 | klf11.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38618168 | KLF11-DT | KLF11 divergent transcript | | 2 | 10041553 | 10043401 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16566121 | AC104794.5 | novel transcript, antisense to KLF11 | | | | | Human | | name | gene, lncrna |