| 2962 | Kcnn1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding; small conductance calcium-activated potassium channel activity; calmodulin binding (ortholog); INVOLVED IN potassium ion transmembrane transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN neuron al cell body; cytoplasm (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 16 | 18608782 | 18632571 | Rat | 80 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731634 | KCNN1 | potassium calcium-activated channel subfamily N member 1 | Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potas sium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008] | 19 | 17951290 | 18000085 | Human | 80 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 735814 | Kcnn1 | potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 | Enables calmodulin binding activity. Predicted to be involved in potassium ion transmembrane transport. Located in cytoplasm and plasma membrane. Is expressed in brain; heart; peripheral nervous system; and testis. Orthologous to human KCNN1 (potassium calcium-a ctivated channel subfamily N member 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 71295802 | 71318335 | Mouse | 80 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8779196 | Kcnn1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN potassium ion transmembrane transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cyt oplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | NW_004955524 | 3323188 | 3344321 | Chinchilla | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11732739 | KCNN1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (inferred); monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inf erred); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | 19 | 17430795 | 17478981 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12068640 | KCNN1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (inferre d); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | 20 | 44939619 | 44971923 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12477014 | Kcnn1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (inferre d); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | NW_004936596 | 3107631 | 3123433 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18595029 | KCNN1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (inferre d); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Green Monkey | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626065469 | Kcnn1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits calmodulin binding (ortholog); inward rectifier potassium channel activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN potassium ion transmembrane transport (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cyt oplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Black Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907793 | Kcnn1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits inward rectifier potassium channel activity (ortholog); protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (i nferred); potassium ion transmembrane transport (inferred); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246480 | kcnn1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13888534 | KCNN1 | potassium calcium-activated channel subfamily N member 1 | ENCODES a protein that exhibits protein-containing complex binding (ortholog); small conductance calcium-activated potassium channel activity (ortholog); INVOLVED IN monoatomic ion transmembrane transport (inferred); monoatomic ion transport (inferred); potassium ion transmembrane transport (inferre d); PARTICIPATES IN calcium/calcium-mediated signaling pathway; FOUND IN cytoplasm (ortholog); neuronal cell body (ortholog); plasma membrane (ortholog) | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155256497 | kcnn1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246479 | kcnn1.S | | | | | | African Clawed Frog | | symbol | gene, null |
