Kcna2 Gene Search Result

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17 records found for search term Kcna2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
2950	Kcna2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits delayed rectifier potassium channel activity; kinesin binding; outward rectifier potassium channel activity; INVOLVED IN cerebral cortex development; corpus callosum development; neuronal action potential; ASSOCIATED WITH Experimental Diabetes Mellitus; autism spectru ... (more) m disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); FOUND IN calyx of Held; glutamatergic synapse; juxtaparanode region of axon; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 6-propyl-2-thiouracil	2	197392746	197406606	Rat	214	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
10830	Kcna2	potassium voltage-gated channel, shaker-related subfamily, member 2	Enables voltage-gated potassium channel activity. Involved in potassium ion transmembrane transport; regulation of circadian sleep/wake cycle, non-REM sleep; and regulation of dopamine secretion. Acts upstream of or within optic nerve structural organization. Located in several cellular components, ... (more) including axon; neuronal cell body membrane; and perikaryon. Part of voltage-gated potassium channel complex. Is active in axon initial segment. Is expressed in several structures, including brain; heart ventricle; and hindlimb muscle. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 32. Orthologous to human KCNA2 (potassium voltage-gated channel subfamily A member 2). [provided by Alliance of Genome Resources, Jul 2025]	3	106998203	107022321	Mouse	239	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
735518	KCNA2	potassium voltage-gated channel subfamily A member 2	Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscl ... (more) e contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. The coding region of this gene is intronless, and the gene is clustered with genes KCNA3 and KCNA10 on chromosome 1. [provided by RefSeq, Jul 2008]	1	110593580	110631440	Human	307	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
8714239	Kcna2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum development (ortholog); neuronal action potential (ortholo ... (more) g); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); axon terminus (ortholog)	NW_004955435	14074346	14080026	Chinchilla	73	symbol	gene, protein-coding, MODEL [RefSeq]
11771955	KCNA2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum ... (more) development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); lamellipodium (ortholog)	1	113187158	113256260	Bonobo	85	symbol	gene, protein-coding, MODEL [RefSeq]
12235737	KCNA2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits voltage-gated potassium channel activity; delayed rectifier potassium channel activity (ortholog); kinesin binding (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum development (ortholog); neuronal action potential (ortholog); ASSOCIATED ... (more) WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); calyx of Held (ortholog)	6	41405453	41415727	Dog	102	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
12692265	Kcna2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum ... (more) development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); lamellipodium (ortholog)	NW_004936704	2007577	2019520	Squirrel	88	symbol	gene, protein-coding, MODEL [RefSeq]
18426534	KCNA2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum ... (more) development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); lamellipodium (ortholog)				Green Monkey	85	symbol	gene, protein-coding, MODEL [RefSeq]
14184349	KCNA2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum ... (more) development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN calyx of Held (ortholog); glutamatergic synapse (ortholog); lamellipodium (ortholog)				Pig	85	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
626063510	Kcna2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits delayed rectifier potassium channel activity (ortholog); kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum development (ortholog); neuronal action potential (ortholo ... (more) g); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); axon terminus (ortholog)				Black Rat	73	symbol	gene, protein-coding, MODEL [RefSeq]
18912801	Kcna2	potassium voltage-gated channel subfamily A member 2	ENCODES a protein that exhibits kinesin binding (ortholog); outward rectifier potassium channel activity (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); INVOLVED IN cerebral cortex development (ortholog); corpus callosum ... (more) development (ortholog); neuronal action potential (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); developmental and epileptic encephalopathy 1 (ortholog); developmental and epileptic encephalopathy 11 (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); calyx of Held (ortholog)				Naked Mole-Rat	81	symbol	gene, protein-coding, MODEL [RefSeq]
155241076	kcna2						Tropical Clawed Frog		symbol	gene, null
155254654	kcna2.L						African Clawed Frog		symbol	gene, null
155241077	kcna2.S						African Clawed Frog		symbol	gene, null
1354203	KCNAB2	potassium voltage-gated channel subfamily A regulatory beta subunit 2	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte tran ... (more) sport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]	1	5992676	6101180	Human	251	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1312242	KCNA10	potassium voltage-gated channel subfamily A member 10	Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscl ... (more) e contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]	1	110517217	110519175	Human	49	description	gene, protein-coding, REVIEWED [RefSeq]
1342945	KCNA3	potassium voltage-gated channel subfamily A member 3	Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscl ... (more) e contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]	1	110653560	110674940	Human	117	description	gene, protein-coding, REVIEWED [RefSeq]