Jag2 Gene Search Result

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14 records found for search term Jag2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
2938	Jag2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits growth factor activity (ortholog); Notch binding (ortholog); INVOLVED IN male gonad development; response to hypoxia; spermatogenesis; PARTICIPATES IN altered Notch signaling pathway; Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH autosomal recessiv ... (more) e limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm; membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione	6	137804133	137826738	Rat	180	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
733495	JAG2	jagged canonical Notch ligand 2	The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that a ... (more) ctivate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]	14	105140995	105168776	Human	194	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
736241	Jag2	jagged 2	Enables Notch binding activity. Involved in auditory receptor cell fate commitment; gamma-delta T cell differentiation; and positive regulation of Notch signaling pathway. Acts upstream of or within several processes, including epithelial cell apoptotic process involved in palatal shelf morphogenesi ... (more) s; odontogenesis of dentin-containing tooth; and respiratory system process. Located in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and surface ectoderm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy. Orthologous to human JAG2 (jagged canonical Notch ligand 2). [provided by Alliance of Genome Resources, Jul 2025]	12	112871439	112893437	Mouse	226	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8929604	Jag2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits growth factor activity (ortholog); Notch binding (ortholog); INVOLVED IN auditory receptor cell fate commitment (ortholog); cell differentiation (ortholog); epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); PARTICIPATES IN Notch sig ... (more) naling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); perinuclear region of cytoplasm (ortholog)	NW_004955538	3421685	3433829	Chinchilla	38	symbol	gene, protein-coding, MODEL [RefSeq]
11962599	JAG2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits calcium ion binding (inferred); growth factor activity (inferred); Notch binding (inferred); INVOLVED IN epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ... (more) PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)	14	85785586	85812056	Bonobo	47	symbol	gene, protein-coding, MODEL [RefSeq]
12375852	JAG2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits calcium ion binding (inferred); growth factor activity (inferred); Notch binding (inferred); INVOLVED IN epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ... (more) PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)	8	72535539	72553531	Dog	45	symbol	gene, protein-coding, MODEL [RefSeq]
12496708	Jag2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits calcium ion binding (inferred); growth factor activity (inferred); Notch binding (inferred); INVOLVED IN epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ... (more) PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)	NW_004936621	363489	380616	Squirrel	45	symbol	gene, protein-coding, MODEL [RefSeq]
625960182	Jag2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits growth factor activity (ortholog); Notch binding (ortholog); INVOLVED IN auditory receptor cell fate commitment (ortholog); cell differentiation (ortholog); epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); PARTICIPATES IN Notch sig ... (more) naling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cytosol (ortholog); membrane (ortholog); perinuclear region of cytoplasm (ortholog)				Black Rat	38	symbol	gene, protein-coding, MODEL [RefSeq]
13893577	JAG2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits calcium ion binding (inferred); growth factor activity (inferred); Notch binding (inferred); INVOLVED IN epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ... (more) PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)				Pig	45	symbol	gene, protein-coding, MODEL [RefSeq]
18576464	JAG2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits calcium ion binding (inferred); growth factor activity (inferred); Notch binding (inferred); INVOLVED IN epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); in utero embryonic development (ortholog); male gonad development (ortholog); ... (more) PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog)				Green Monkey	47	symbol	gene, protein-coding, MODEL [RefSeq]
284586351	jag2						Tropical Clawed Frog		symbol	gene, null
18901978	Jag2	jagged canonical Notch ligand 2	ENCODES a protein that exhibits growth factor activity (ortholog); INVOLVED IN auditory receptor cell fate commitment (ortholog); cell differentiation (ortholog); epithelial cell apoptotic process involved in palatal shelf morphogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED ... (more) WITH autosomal recessive limb-girdle muscular dystrophy type 27 (ortholog); Breast Neoplasms (ortholog); Craniofacial Abnormalities (ortholog); FOUND IN cytosol (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)				Naked Mole-Rat	44	symbol	gene, protein-coding, MODEL [RefSeq]
284886543	jag2.L						African Clawed Frog		symbol	gene, null
285064208	jag2.S						African Clawed Frog		symbol	gene, null