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Gene: JAG2 (jagged canonical Notch ligand 2) Homo sapiens
Symbol: JAG2
Name: jagged canonical Notch ligand 2
Description: Exhibits Notch binding activity and growth factor activity. Involved in regulation of cell population proliferation; spermatogenesis; and thymic T cell selection. Predicted to localize to integral component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: HJ2; jagged 2; protein jagged-2; SER2
Mus musculus (house mouse) : Jag2 (jagged 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Jag2 (jagged canonical Notch ligand 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Jag2 (jagged canonical Notch ligand 2)
Pan paniscus (bonobo/pygmy chimpanzee) : JAG2 (jagged canonical Notch ligand 2)
Canis lupus familiaris (dog) : JAG2 (jagged canonical Notch ligand 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Jag2 (jagged canonical Notch ligand 2)
Sus scrofa (pig) : JAG2 (jagged canonical Notch ligand 2)
Chlorocebus sabaeus (African green monkey) : JAG2 (jagged canonical Notch ligand 2)
Heterocephalus glaber (naked mole-rat) : Jag2 (jagged canonical Notch ligand 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl14105,140,982 - 105,168,824 (-)EnsemblGRCh38hg38GRCh38
GRCh3814105,140,981 - 105,168,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714105,607,318 - 105,635,161 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614104,679,121 - 104,706,206 (-)NCBINCBI36hg18NCBI36
Build 3414104,679,120 - 104,706,206NCBI
Celera1485,661,503 - 85,688,392 (-)NCBI
Cytogenetic Map14q32.33NCBI
HuRef1485,798,697 - 85,815,481 (-)NCBIHuRef
CHM1_114105,545,299 - 105,572,922 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on JAG2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733495
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.