| 71075 | Itgad | integrin subunit alpha D | ENCODES a protein that exhibits protein-containing complex binding; cell adhesion receptor activity (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell-cell adhesion mediated by integrin (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated sign aling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN integrin alphaD-beta2 complex (ortholog); plasma membrane (ortholog); INTERACTS WITH acetamide; ammonium chloride; amphetamine | 1 | 192190204 | 192218864 | Rat | 63 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731798 | ITGAD | integrin subunit alpha D | This gene belongs to the beta-2 integrin family of membrane glycoproteins, which are are composed of non-covalently linked alpha and beta subunits to form a heterodimer. It encodes the alpha subunit of the cell surface heterodimers and is involved in the activation and adhesion functions of leukocyt es. The gene is located about 11kb downstream of the integrin subunit alpha X gene, another member of the integrin family. It is expressed in the tissue and circulating myeloid leukocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] | 16 | 31393335 | 31426505 | Human | 67 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1615517 | Itgad | integrin, alpha D | Predicted to enable integrin binding activity. Acts upstream of or within activated T cell proliferation. Predicted to be part of integrin complex. Predicted to be active in external side of plasma membrane. Orthologous to human ITGAD (integrin subunit alpha D). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 127773105 | 127822988 | Mouse | 72 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8881085 | Itgad | integrin subunit alpha D | ENCODES a protein that exhibits cell adhesion receptor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell-cell adhesion mediated by integrin (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN integrin me diated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN integrin alphaD-beta2 complex (ortholog); plasma membrane (ortholog) | NW_004955493 | 8233098 | 8260613 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11886561 | ITGAD | integrin subunit alpha D | ENCODES a protein that exhibits cell adhesion receptor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (orth olog); FOUND IN integrin alphaD-beta2 complex (ortholog) | 16 | 23539562 | 23572705 | Bonobo | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12277995 | ITGAD | integrin subunit alpha D | ENCODES a protein that exhibits cell adhesion receptor activity (ortholog); INVOLVED IN cell-cell adhesion mediated by integrin (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN integrin alphaD-beta2 complex (ortholog); plasma membrane (ortholog) | 6 | 16808680 | 16834019 | Dog | 26 | symbol | gene, protein-coding, INFERRED [RefSeq] |
| 12562522 | Itgad | integrin subunit alpha D | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN cell surface (inferred); ext ernal side of plasma membrane (inferred); integrin alphaD-beta2 complex (inferred) | NW_004936543 | 8382942 | 8412486 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285258480 | itgad | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18744007 | ITGAD | integrin subunit alpha D | ENCODES a protein that exhibits cell adhesion receptor activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); cell-cell adhesion mediated by integrin (ortholog); heterotypic cell-cell adhesion (ortholog); PARTICIPATES IN integrin me diated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN integrin alphaD-beta2 complex (ortholog); plasma membrane (ortholog) | | | | Green Monkey | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14293858 | ITGAD | integrin subunit alpha D | ENCODES a protein that exhibits protein-containing complex binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH lung adenocarcinoma (ortholog); prostate cancer (ortholog); FOUND IN cell surface (inferred); int egrin alphaD-beta2 complex (inferred); integrin complex (inferred) | | | | Pig | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 628374387 | itgad.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 2926 | Itgam | integrin subunit alpha M | ENCODES a protein that exhibits protein-containing complex binding; cargo receptor activity (ortholog); cell adhesion receptor activity (ortholog); INVOLVED IN heterotypic cell-cell adhesion; response to amphetamine; response to curcumin; PARTICIPATES IN integrin mediated signaling pathway; Entamoeb iasis pathway; Leishmaniasis pathway; ASSOCIATED WITH Acute Lung Injury; Brain Death; brain ischemia; FOUND IN cell surface; external side of plasma membrane (ortholog); extracellular space (ortholog); INTERACTS WITH (R,R,R)-alpha-tocopherol; 1-naphthyl isothiocyanate; 17beta-estradiol | 1 | 192089496 | 192139947 | Rat | 529 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |