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33 records found for search term Irak1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1348457IRAK1interleukin 1 receptor associated kinase 1This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. AlterX154010507154019902Human419symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1557574Irak1interleukin-1 receptor-associated kinase 1Enables interleukin-1 receptor binding activity and protein kinase activity. Involved in several processes, including interleukin-1-mediated signaling pathway; negative regulation of cholesterol efflux; and positive regulation of JUN kinase activity. Acts upstream of or within several processes, incX7305752073067527Mouse317symbol , PhenoGen , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1563841Irak1interleukin-1 receptor-associated kinase 1ENCODES a protein that exhibits heat shock protein binding; protein kinase activity; identical protein binding (ortholog); INVOLVED IN cellular response to heat; cellular response to hypoxia; cellular response to lipopolysaccharide; PARTICIPATES IN interleukin-1 signaling pathway; Toll-like receptorX156919927156929825Rat317symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
9000084Irak1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); identical protein binding (ortholog); interleukin-1 receptor binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); cellular response to heat (ortholog); cellular response to hypoxia (ortholog); PARTINW_004955580663651668622Chinchilla106symbolgene, protein-coding, MODEL [RefSeq]
12028774IRAK1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIX143560802143570185Bonobo125symbolgene, protein-coding, MODEL [RefSeq]
12332689IRAK1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIX121853340121862582Dog134symbolgene, protein-coding, MODEL [RefSeq]
12454606Irak1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICINW_004936809891407900311Squirrel125symbolgene, protein-coding, MODEL [RefSeq]
13941400IRAK1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIPig135symbolgene, protein-coding, MODEL [RefSeq]
18512781IRAK1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); interleukin-1 receptor binding (ortholog); protein kinase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); cellular response to hypoxia (ortholog); cellular response to lipopolysaccharide (ortholog); PARTICIGreen Monkey124symbolgene, protein-coding, MODEL [RefSeq]
18901581Irak1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); identical protein binding (ortholog); interleukin-1 receptor binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); cellular response to heat (ortholog); cellular response to hypoxia (ortholog); PARTINaked Mole-Rat117symbolgene, protein-coding, MODEL [RefSeq]
155252091irak1Tropical Clawed Frogsymbolgene, null
625976961Irak1interleukin 1 receptor associated kinase 1ENCODES a protein that exhibits heat shock protein binding (ortholog); identical protein binding (ortholog); interleukin-1 receptor binding (ortholog); INVOLVED IN canonical NF-kappaB signal transduction (ortholog); cellular response to heat (ortholog); cellular response to hypoxia (ortholog); PARTIBlack Rat106symbolgene, protein-coding, MODEL [RefSeq]
155256821irak1.LAfrican Clawed Frogsymbolgene, null
405860409irak1.SAfrican Clawed Frogsymbolgene, null
405860568irak1.SAfrican Clawed Frogsymbolgene, null
405860736irak1.SAfrican Clawed Frogsymbolgene, null
405865593irak1.SAfrican Clawed Frogsymbolgene, null
626182785irak1.SAfrican Clawed Frogsymbolgene, null
1312787IRAK1BP1interleukin 1 receptor associated kinase 1 binding protein 1Predicted to enable signaling adaptor activity. Predicted to be involved in canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]67886755178979411Human82symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, VALIDATED [RefSeq]
1312788Irak1bp1interleukin-1 receptor-associated kinase 1 binding protein 1Enables signaling adaptor activity. Involved in positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human IRAK198271185982729741Mouse80symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
1305012Irak1bp1interleukin-1 receptor-associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES (ortholog); Sjogren's syndrome (ortholog); FOUN89260846892628377Rat82symbol , PhenoGengene, protein-coding, VALIDATED [RefSeq]
8725963Irak1bp1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES (ortholog); Sjogren's syndrome (ortholog)NW_00495550268005326811214Chinchilla6symbolgene, protein-coding, MODEL [RefSeq]
11807063IRAK1BP1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND67671723476751725Bonobo11symbolgene, protein-coding, MODEL [RefSeq]
12164153IRAK1BP1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND123985733139883471Dog11symbolgene, protein-coding, MODEL [RefSeq]
12638495Irak1bp1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, ANDNW_0049365101122019411242485Squirrel11symbolgene, protein-coding, MODEL [RefSeq]
13875315IRAK1BP1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits kinase activity (inferred); signaling adaptor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTPig12symbolgene, protein-coding, MODEL [RefSeq]
18575665IRAK1BP1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (inferred); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, ANDGreen Monkey11symbolgene, protein-coding, MODEL [RefSeq]
18923534Irak1bp1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN DNA-templated transcription (inferred); immune response (inferred); positive regulation of canonical NF-kappaB signal transduction (inferred); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, ANDNaked Mole-Rat11symbolgene, protein-coding, MODEL [RefSeq]
155247850irak1bp1Tropical Clawed Frogsymbolgene, null
626143923Irak1bp1interleukin 1 receptor associated kinase 1 binding protein 1ENCODES a protein that exhibits signaling adaptor activity (ortholog); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH DEVELOPMENTAL DELAY, INTELLECTUAL DISABILITY, OBESITY, AND DYSMORPHIC FEATURES (ortholog); Sjogren's syndrome (ortholog)Black Rat6symbolgene, protein-coding, MODEL [RefSeq]
155247849irak1bp1.SAfrican Clawed Frogsymbolgene, null
1605259PELI3pellino E3 ubiquitin protein ligase family member 3The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcrip116646632766477337Human75descriptiongene, protein-coding, REVIEWED [RefSeq]
1315706TRAF6TNF receptor associated factor 6The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein has an amino terminal RING domain which is followed by four zinc-fi113648376936510272Human420descriptiongene, protein-coding, REVIEWED [RefSeq]