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Pathways
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10 records found for search term Ikbkap
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
620072Elp1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding; protein kinase activity; INVOLVED IN I-kappaB phosphorylation; tRNA wobble uridine modification (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Gaucher's disease (ortholog); FOUND IN cytoplasm (ortholog); c57624854576300985Rat143old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
734035ELP1elongator acetyltransferase complex subunit 1The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations 9108867517108934124Human598old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
734036Elp1elongator complex protein 1Predicted to enable ATP binding activity; protein kinase activity; and tRNA binding activity. Involved in tRNA wobble uridine modification. Located in cytoplasm. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study Riley-Day syndrome and h45674654756802565Mouse285old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
8892359Elp1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); tRNA wobble uridine modification (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Gaucher's disease (ortholog);NW_0049554191803519718097681Chinchilla32old_gene_symbolgene, protein-coding, MODEL [RefSeq]
11668347ELP1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH asthma (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); elon98002013180085076Bonobo40old_gene_symbolgene, protein-coding, MODEL [RefSeq]
12088032ELP1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH asthma (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); elon116403566764094402Dog40old_gene_symbolgene, protein-coding, MODEL [RefSeq]
12704700Elp1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH asthma (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); elonNW_00493655939241853981907Squirrel40old_gene_symbolgene, protein-coding, MODEL [RefSeq]
18903306Elp1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Gaucher's disease (ortholog); FOUND IN nucleoplasm (ortholog)Naked Mole-Rat36old_gene_symbolgene, protein-coding, MODEL [RefSeq]
13986494ELP1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH asthma (ortholog); Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); elonPig39old_gene_symbolgene, protein-coding, MODEL [RefSeq]
18516282ELP1elongator acetyltransferase complex subunit 1ENCODES a protein that exhibits ATP binding (ortholog); protein kinase activity (ortholog); INVOLVED IN I-kappaB phosphorylation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Charcot-Marie-Tooth disease (ortholog); Gaucher's disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (infeGreen Monkey40old_gene_symbolgene, protein-coding, MODEL [RefSeq]