| 620599 | Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits RNA sequestering activity (ortholog); INVOLVED IN cellular response to interferon-alpha (ortholog); cellular response to interferon-beta (ortholog); negative regulation of viral translation (ortholog); PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH COVID-19 (ort holog); High Myopia (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; acetamide | 1 | 241565197 | 241567262 | Rat | 138 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733854 | Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | Predicted to enable RNA binding activity. Involved in response to virus. Acts upstream of or within cellular response to interferon-alpha; cellular response to interferon-beta; and response to bacterium. Located in cytoplasm. Is expressed in several structures, including alimentary system; cardiovas cular system; eye; genitourinary system; and nervous system. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratricopeptide repeats 1B). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 34618289 | 34627409 | Mouse | 150 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1312562 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 | This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely relate d genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] | 10 | 89392623 | 89406487 | Human | 184 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 9057989 | Ifit1 | interferon induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits enzyme inhibitor activity (ortholog); RNA binding (ortholog); RNA sequestering activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); cellular response to exogenous dsRNA (ortholog); cellular response to type I interferon (ortholog); ASSOCIATED WITH endometriosis (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | NW_004955425 | 3581705 | 3588528 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18640467 | IFIT1 | interferon induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); RNA binding (inferred); RNA sequestering activity (inferred); INVOLVED IN antiviral innate immune response (inferred); cellular response to exogenous dsRNA (inferred); cellular response to type I interferon (inferred); ASSOCIATED WITH endometriosis (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); host cell (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1304872 | Ifit1bl | interferon-induced protein with tetratricopeptide repeats 1B-like | INVOLVED IN response to other organism (inferred); PARTICIPATES IN hepatitis C pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine | 1 | 241535776 | 241580476 | Rat | 17 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 13848571 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); RNA binding (inferred); RNA sequestering activity (inferred); INVOLVED IN antiviral innate immune response (inferred); cellular response to exogenous dsRNA (inferred); cellular response to type I interferon (inferred); ASSOCIATED WITH endometriosis (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); host cell (inferred); INTERACTS WITH chloroquine; deoxynivalenol; graphene oxide | | | | Pig | 35 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11802862 | LOC100976728 | interferon-induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); RNA binding (inferred); RNA sequestering activity (inferred); INVOLVED IN antiviral innate immune response (inferred); cellular response to exogenous dsRNA (inferred); cellular response to type I interferon (inferred); ASSOCIATED WITH endometriosis (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); host cell (inferred) | 10 | 86117807 | 86129256 | Bonobo | 27 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903867 | LOC101701903 | interferon-induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN defense response to virus (inferred); response to other organism (inferred); FOUND IN cytosol (inferred) | | | | Naked Mole-Rat | 4 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12662474 | LOC101970383 | interferon-induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN defense response to virus (inferred); response to other organism (inferred); FOUND IN cytosol (inferred) | NW_004936601 | 4796139 | 4803171 | Squirrel | 4 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12300469 | LOC488947 | interferon-induced protein with tetratricopeptide repeats 1 | ENCODES a protein that exhibits enzyme inhibitor activity (ortholog); RNA sequestering activity (ortholog); INVOLVED IN cellular response to exogenous dsRNA (ortholog); cellular response to type I interferon (ortholog); intracellular transport of viral protein in host cell (ortholog); ASSOCIATED WIT H endometriosis (ortholog); Human Influenza (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog) | 4 | 125675 | 133304 | Dog | 26 | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1344579 | IFIT1B | interferon induced protein with tetratricopeptide repeats 1B | Predicted to enable RNA binding activity. Predicted to be involved in defense response to virus. Predicted to act upstream of or within cellular response to interferon-alpha; cellular response to interferon-beta; and response to bacterium. Predicted to be located in cytoplasm. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Jul 2025] | 10 | 89378056 | 89385205 | Human | 130 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 329332966 | ifit1b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20867437 | IFIT1B | interferon induced protein with tetratricopeptide repeats 1B | | | | | Green Monkey | | symbol | gene, protein-coding |
| 18738583 | IFIT1B | interferon induced protein with tetratricopeptide repeats 1B | ENCODES a protein that exhibits RNA sequestering activity (ortholog); INVOLVED IN cellular response to interferon-alpha (ortholog); cellular response to interferon-beta (ortholog); negative regulation of viral translation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); High Myopia (ortholog); FOUND IN cytoplasm (ortholog) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1342851 | IFIT1P1 | interferon induced protein with tetratricopeptide repeats 1 pseudogene 1 | INTERACTS WITH lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine | 13 | 32384602 | 32386641 | Human | 4 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 329328976 | ifit1b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1620177 | Ifit1bl1 | interferon induced protein with tetratricpeptide repeats 1B like 1 | Predicted to enable RNA binding activity. Predicted to be involved in defense response to virus. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratr icopeptide repeats 1B). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 34570288 | 34640382 | Mouse | 44 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1312563 | Ifit1bl2 | interferon induced protein with tetratricopeptide repeats 1B like 2 | Predicted to enable RNA binding activity. Predicted to be involved in defense response to virus. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Orthologous to several human genes including IFIT1B (interferon induced protein with tetratr icopeptide repeats 1B). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 34594446 | 34618163 | Mouse | 24 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 13944672 | IFIT3 | interferon induced protein with tetratricopeptide repeats 3 | ENCODES a protein that exhibits enzyme inhibitor activity (inferred); identical protein binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); response to bacterium (ortholog); response to stilbenoid (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); congestive heart failure (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); host cell (inferred) | | | | Pig | 49 | ensembl_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12038968 | LOC100977291 | interferon-induced protein with tetratricopeptide repeats 1B | ENCODES a protein that exhibits RNA sequestering activity (ortholog); INVOLVED IN cellular response to interferon-alpha (ortholog); cellular response to interferon-beta (ortholog); negative regulation of viral translation (ortholog); ASSOCIATED WITH COVID-19 (ortholog); High Myopia (ortholog); FOUND IN cytoplasm (ortholog) | 10 | 86094636 | 86109924 | Bonobo | 20 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934070 | LOC101715397 | interferon-induced protein with tetratricopeptide repeats 1B | ENCODES a protein that exhibits RNA binding (inferred); INVOLVED IN cellular response to interferon-alpha (inferred); defense response to virus (inferred); immune system process (inferred); FOUND IN cytosol (inferred) | | | | Naked Mole-Rat | 8 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12651564 | LOC101971247 | interferon-induced protein with tetratricopeptide repeats 1B | | NW_004936601 | 4871781 | 4885107 | Squirrel | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8796326 | LOC102017584 | interferon-induced protein with tetratricopeptide repeats 1B | | NW_004955425 | 3606058 | 3611013 | Chinchilla | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12084849 | LOC606817 | interferon-induced protein with tetratricopeptide repeats 1B | | 4 | 115334 | 117225 | Dog | | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |