| 1305039 | Icam5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN cell-cell adhesion mediated by integrin (ortholog); homophilic cell-cell adhesion (ortholog); phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (ortholog); dendritic spine membrane (ortholog); glutamatergic synapse (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 17beta-estradiol 3-benzoate | 8 | 27843563 | 27851767 | Rat | 111 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312830 | ICAM5 | intercellular adhesion molecule 5 | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases. [provided by RefSeq, Jul 2008] | 19 | 10289952 | 10296778 | Human | 116 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312831 | Icam5 | intercellular adhesion molecule 5, telencephalin | Predicted to enable integrin binding activity. Involved in regulation of synapse assembly. Acts upstream of or within phagocytosis. Located in plasma membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in brain. Orthologous to human ICAM5 (intercellular adhesion molecule 5). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 20943372 | 20950331 | Mouse | 117 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9021627 | Icam5 | intercellular adhesion molecule 5 | INVOLVED IN cell-cell adhesion mediated by integrin (ortholog); homophilic cell-cell adhesion (ortholog); phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (ortholog); dendritic spine membrane (ortholo g); glutamatergic synapse (ortholog) | NW_004955495 | 1575669 | 1583904 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11697077 | ICAM5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); protein-containing complex binding (inferred); INVOLVED IN phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (inferred); dendritic spine mem brane (inferred); glutamatergic synapse (inferred) | 19 | 9839821 | 9847198 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12261333 | ICAM5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (inferred); dendritic spine membrane (inferred); glutamatergic synapse (inferr ed) | 20 | 50809065 | 50816015 | Dog | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12504969 | Icam5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (inferred); dendritic spine membrane (inferred); glutamatergic synapse (inferr ed) | NW_004936659 | 630177 | 636586 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284244767 | icam5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18387784 | ICAM5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (inferred); dendritic spine membrane (inferred); glutamatergic synapse (inferr ed) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13871825 | ICAM5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (inferred); dendritic spine membrane (inferred); glutamatergic synapse (inferr ed) | | | | Pig | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903560 | Icam5 | intercellular adhesion molecule 5 | ENCODES a protein that exhibits integrin binding (inferred); INVOLVED IN cell-cell adhesion mediated by integrin (ortholog); homophilic cell-cell adhesion (ortholog); phagocytosis (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Colorectal Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN cell projection (ortholog); dendritic spine membrane (ortholog); glutamatergic synapse (ortholog) | | | | Naked Mole-Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285927086 | icam5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284244930 | icam5.S | | | | | | African Clawed Frog | | symbol | gene, null |