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16 records found for search term Hgd
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1308757Hgdhomogentisate 1, 2-dioxygenaseENCODES a protein that exhibits homogentisate 1,2-dioxygenase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); L-tyrosine catabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine b117659220276643776Rat143symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1318713HGDhomogentisate 1,2-dioxygenaseThis gene encodes the enzyme homogentisate 1,2 dioxygenase. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria.[provided by RefSeq, May 2010]3120628172120682239Human329symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1318714Hgdhomogentisate 1, 2-dioxygenaseEnables homogentisate 1,2-dioxygenase activity. Acts upstream of or within amino acid metabolic process. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and sensory organ. Used to study alkaptonuria. Human ortholog(s) of this gene implicated in al163740010437452388Mouse156symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8720242Hgdhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits homogentisate 1,2-dioxygenase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); L-tyrosine catabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine bNW_0049554272014152220188700Chinchilla20symbolgene, protein-coding, MODEL [RefSeq]
11815081HGDhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits dioxygenase activity (inferred); homogentisate 1,2-dioxygenase activity (inferred); identical protein binding (inferred); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydr3117735772117790096Bonobo34symbolgene, protein-coding, MODEL [RefSeq]
12152193HGDhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits dioxygenase activity (inferred); GTP binding (inferred); homogentisate 1,2-dioxygenase activity (inferred); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase defici332406609924107827Dog35symbolgene, protein-coding, MODEL [RefSeq]
12667309Hgdhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits dioxygenase activity (inferred); homogentisate 1,2-dioxygenase activity (inferred); identical protein binding (inferred); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydrNW_00493653673145487359426Squirrel34symbolgene, protein-coding, MODEL [RefSeq]
285093904hgdTropical Clawed Frogsymbolgene, null
625997463Hgdhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits homogentisate 1,2-dioxygenase activity (ortholog); identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); L-tyrosine catabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine bBlack Rat20symbolgene, protein-coding, MODEL [RefSeq]
18907109Hgdhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydroxylase deficiency pathway; ASSOCIATED WITH alkaptonuria (ortholog); Alkaptonuric OcNaked Mole-Rat32symbolgene, protein-coding, MODEL [RefSeq]
18449296HGDhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits dioxygenase activity (inferred); homogentisate 1,2-dioxygenase activity (inferred); identical protein binding (inferred); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydrGreen Monkey34symbolgene, protein-coding, MODEL [RefSeq]
14290352HGDhomogentisate 1,2-dioxygenaseENCODES a protein that exhibits dioxygenase activity (inferred); homogentisate 1,2-dioxygenase activity (inferred); identical protein binding (inferred); INVOLVED IN amino acid metabolic process (ortholog); PARTICIPATES IN alkaptonuria pathway; disulfiram pharmacodynamics pathway; dopamine beta-hydrPig33symbolgene, protein-coding, MODEL [RefSeq]
286397049hgd.LAfrican Clawed Frogsymbolgene, null
12411426RABL3RAB, member of RAS oncogene family like 3ENCODES a protein that exhibits G protein activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN B cell differentiation (ortholog); natural killer cell differentiation (ortholog); positive regulation of cilium assembly (ortholog); ASSOCIATED WITH pancreatic cancer (ortholog)332410775424151378Dog28ensembl_gene_symbolgene, protein-coding, MODEL [RefSeq]
735823GDNFglial cell derived neurotrophic factorThis gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is53781267737840041Human504old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]
733213GLUD1glutamate dehydrogenase 1This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and 108705020287094843Human344old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]