| 1306765 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); gamete generation (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A | 1 | 93598076 | 93601598 | Rat | 48 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315571 | GGN | gametogenetin | This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin p rotein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008] | 19 | 38384267 | 38388384 | Human | 53 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1618107 | Ggn | gametogenetin | Enables identical protein binding activity and ubiquitin protein ligase binding activity. Involved in gamete generation. Acts upstream of or within double-strand break repair; embryo implantation; and protein localization. Located in perinuclear region of cytoplasm. Is expressed in brain; early conc eptus; eye; gonad; and metanephros. Human ortholog(s) of this gene implicated in spermatogenic failure 69. Orthologous to human GGN (gametogenetin). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 28869635 | 28873363 | Mouse | 59 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8714770 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); gamete generation (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog) | NW_004955468 | 1039531 | 1044513 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12005677 | GGN | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortho log); perinuclear region of cytoplasm (ortholog) | 19 | 35477933 | 35482380 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12338319 | GGN | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FO UND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog) | 1 | 114615817 | 114618950 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12707584 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortho log); perinuclear region of cytoplasm (ortholog) | NW_004936801 | 1144400 | 1148228 | Squirrel | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14137392 | GGN | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortho log); perinuclear region of cytoplasm (ortholog) | | | | Pig | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18665577 | GGN | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortho log); perinuclear region of cytoplasm (ortholog) | | | | Green Monkey | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18920218 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortho log); perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866003 | GGN | gametogenetin | | | | | Green Monkey | | symbol | gene, protein-coding |
| 150657596 | GGN | gametotin | INVOLVED IN double-strand break repair (inferred); gamete generation (inferred) | | | | Dog | 3 | symbol | gene, protein-coding |
| 625929174 | Ggn | gametogenetin | ENCODES a protein that exhibits identical protein binding (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN double-strand break repair (ortholog); embryo implantation (ortholog); gamete generation (ortholog); ASSOCIATED WITH spermatogenic failure 69 (ortholog); FOUND IN cytoplasm (ortholog); nucleolus (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 16564439 | AC005789.1 | novel transcript, antisense to GGN | | | | | Human | | name | gene, lncrna |
| 1346891 | MT-TG | mitochondrially encoded tRNA-Gly (GGN) | ASSOCIATED WITH Exercise Intolerance; Exercise intolerance; familial hypertrophic cardiomyopathy; INTERACTS WITH valproic acid | MT | 9991 | 10058 | Human | 16 | name | gene, trna |
| 1359729 | Ggnbp1 | gametogenetin binding protein 1 | INVOLVED IN mitochondrial fission (ortholog); FOUND IN Golgi apparatus (ortholog); mitochondrial intermembrane space (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol | 20 | 5111734 | 5118034 | Rat | 49 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1619991 | Ggnbp1 | gametogenetin binding protein 1 | Involved in mitochondrial fission. Located in Golgi apparatus; mitochondrial intermembrane space; and plasma membrane. Is expressed in ductus deferens; epididymis; jejunum; and testis. Orthologous to human GGNBP1 (gametogenetin binding protein 1 (pseudogene)). [ provided by Alliance of Genome Resources, Jul 2025] | 17 | 27237009 | 27255352 | Mouse | 53 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1642110 | GGNBP1 | gametogenetin binding protein 1 (pseudogene) | This gene is the ortholog of the mouse gametogenetin-binding protein 1 gene. In human, the open reading frame is disrupted by a nonsense mutation after 8-aa; consequently, this gene is currently considered to be a unitary pseudogene in human even though it is functional in other mammals. [provided b y RefSeq, Aug 2009] | 6 | 33583699 | 33589026 | Human | 42 | symbol , COSMIC , Human Proteome Map | gene, pseudo, REVIEWED [RefSeq] |
| 13367737 | GGNBP1 | gametogenetin binding protein 1 | INVOLVED IN mitochondrial fission (ortholog); FOUND IN mitochondrial intermembrane space (ortholog); plasma membrane (ortholog) | 12 | 2949364 | 2970699 | Dog | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13879503 | GGNBP1 | gametogenetin binding protein 1 | INVOLVED IN mitochondrial fission (ortholog); FOUND IN Golgi apparatus (ortholog); mitochondrial intermembrane space (ortholog); plasma membrane (ortholog) | | | | Pig | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 1302978 | Ggnbp2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisph enol A; resveratrol | 10 | 70208950 | 70240554 | Rat | 66 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1343556 | GGNBP2 | gametogenetin binding protein 2 | Predicted to be involved in spermatogenesis. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of cell population proliferation; and negative regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in cytoplasmic vesicle. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025] | 17 | 36544919 | 36589848 | Human | 66 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1614194 | Ggnbp2 | gametogenetin binding protein 2 | Acts upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of cell population proliferation; and negative regulation of peptidyl-tyrosine phosphorylation. Located in cytoplasm and nucleus. Is expressed in several structures, including cen tral nervous system; early conceptus; genitourinary system; retina; and spleen. Orthologous to human GGNBP2 (gametogenetin binding protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 84723187 | 84761668 | Mouse | 109 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8895153 | Ggnbp2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | NW_004955451 | 1345720 | 1386100 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11862313 | GGNBP2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | 17 | 20491687 | 20537516 | Bonobo | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12276553 | GGNBP2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | 9 | 36430194 | 36463248 | Dog | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12700749 | Ggnbp2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936490 | 1635443 | 1671057 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14160862 | GGNBP2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Pig | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18664157 | GGNBP2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923932 | Ggnbp2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253675 | ggnbp2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626111571 | Ggnbp2 | gametogenetin binding protein 2 | INVOLVED IN cell differentiation (ortholog); labyrinthine layer blood vessel development (ortholog); labyrinthine layer development (ortholog); ASSOCIATED WITH Developmental Disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155233634 | ggnbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596933856 | ggnbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934196 | ggnbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934709 | ggnbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 596934772 | ggnbp2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155256301 | ggnbp2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 9673427 | Ggnbp2os | gametogenetin binding protein 2, opposite strand | INTERACTS WITH bisphenol F; tetrachloromethane | 11 | 84760831 | 84762457 | Mouse | 2 | symbol , PhenoGen | gene, ncrna, VALIDATED [RefSeq] |
| 1317518 | MED16 | mediator complex subunit 16 | Enables nuclear thyroid hormone receptor binding activity and transcription coactivator activity. Involved in positive regulation of transcription initiation by RNA polymerase II. Located in nucleus. Part of core mediator complex and mediator complex. [provided by Alliance of Genome Resources, Jul 2 025] | 19 | 867963 | 893187 | Human | 86 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 10401763 | SNORD133 | small nucleolar RNA, C/D box 133 | | 12 | 50456571 | 50456786 | Human | | old_gene_symbol | gene, snorna, VALIDATED [RefSeq] |
| 15039076 | mt-Tg | tRNA glycine, mitochondrial | Predicted to enable triplet codon-amino acid adaptor activity. Predicted to act upstream of or within translational elongation. Predicted to be located in mitochondrion. Orthologous to human MT-TG (mitochondrially encoded tRNA-Gly (GGN)). [provided by Alliance o f Genome Resources, Jul 2025] | MT | 9391 | 9458 | Mouse | 10 | description | gene, trna |