| 1316624 | FPR2 | formyl peptide receptor 2 | Enables amyloid-beta binding activity; scavenger receptor binding activity; and signaling receptor activity. Involved in several processes, including cellular response to amyloid-beta; positive regulation of ERK1 and ERK2 cascade; and regulation of defense response. Located in cytoplasm and plasma m embrane. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 51761180 | 51770531 | Human | 151 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1557793 | Fpr2 | formyl peptide receptor 2 | Enables N-formyl peptide receptor activity and amyloid-beta binding activity. Involved in cellular response to amyloid-beta; positive chemotaxis; and positive regulation of superoxide anion generation. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway . Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human FPR2 (formyl peptide receptor 2). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 18108086 | 18114214 | Mouse | 161 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1584013 | Fpr2 | formyl peptide receptor 2 | ENCODES a protein that exhibits cargo receptor activity; RAGE receptor binding; amyloid-beta binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; astrocyte activation; cellular response to amyloid-beta; ASSOCIATED WITH dentin caries; Crohn's dise ase (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm; plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; amphetamine; bisphenol A | 1 | 67449637 | 67458272 | Rat | 137 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 11777343 | FPR2 | formyl peptide receptor 2 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); cargo receptor activity (ortholog); N-formyl peptide receptor activity (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); astrocyte activation (ortholog); calcium-mediated sign aling (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); dentin caries (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog); plasma membrane (ortholog) | 19 | 48663622 | 48715535 | Bonobo | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14373827 | FPR2 | | | | | | Yeast | | symbol | gene, null |
| 625981883 | Fpr2 | formyl peptide receptor 2 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); cargo receptor activity (ortholog); RAGE receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); astrocyte activation (ortholog); calcium-mediated signaling (orthol og); ASSOCIATED WITH Crohn's disease (ortholog); dentin caries (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog) | | | | Black Rat | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18428044 | FPR2 | formyl peptide receptor 2 | ENCODES a protein that exhibits cargo receptor activity (ortholog); RAGE receptor binding (ortholog); INVOLVED IN astrocyte activation (ortholog); dentinogenesis (ortholog); microglial cell activation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); dentin caries (ortholog); lung adenocarcino ma (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | | | | Green Monkey | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900948 | Fpr2 | formyl peptide receptor 2 | ENCODES a protein that exhibits amyloid-beta binding (ortholog); cargo receptor activity (ortholog); RAGE receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); astrocyte activation (ortholog); calcium-mediated signaling (orthol og); ASSOCIATED WITH Crohn's disease (ortholog); dentin caries (ortholog); lung adenocarcinoma (ortholog); FOUND IN cytoplasm (ortholog) | | | | Naked Mole-Rat | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 2320534 | Fpr2-ps1 | formyl peptide receptor 2, pseudogene 1 | | 1 | 67502990 | 67504602 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1584003 | Fpr2-ps2 | formyl peptide receptor 2, pseudogene 2 | | 1 | 67527269 | 67528410 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 11361878 | Fpr2-ps3 | formyl peptide receptor 2, pseudogene 3 | | 1 | 59037155 | 59038160 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1583982 | Fpr2-ps4 | formyl peptide receptor 2, pseudogene 4 | | 1 | 67582001 | 67630129 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 11474511 | Fpr2-ps5 | formyl peptide receptor 2, pseudogene 5 | | 8 | 8470285 | 8471319 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 12378171 | FPR | formyl peptide receptor | ENCODES a protein that exhibits cargo receptor activity (ortholog); RAGE receptor binding (ortholog); INVOLVED IN astrocyte activation (ortholog); dentinogenesis (ortholog); microglial cell activation (ortholog); ASSOCIATED WITH Crohn's disease (ortholog); dentin caries (ortholog); lung adenocarcino ma (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred) | 1 | 105343096 | 105353563 | Dog | 50 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 8904983 | LOC102007821 | N-formyl peptide receptor 2 | | NW_004955558 | 780076 | 787914 | Chinchilla | | ensembl_gene_symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 1309032 | Fpr2l1 | formyl peptide receptor 2 like 1 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); N-formyl peptide receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred); INTERACTS WITH furan; gentamycin; paraceta mol | 1 | 68359518 | 68360549 | Rat | 19 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1310130 | Fpr2l2 | formyl peptide receptor 2 like 2 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred) | 1 | 67670128 | 67671099 | Rat | 7 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1582880 | Fpr2l3 | formyl peptide receptor 2 like 3 | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN G protein-coupled receptor signaling pathway (inferred); signal transduction (inferred); FOUND IN membrane (inferred); INTERACTS WITH bisphenol A | 1 | 67854448 | 67855622 | Rat | 15 | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1614455 | Fpr3 | formyl peptide receptor 3 | Enables signaling receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to several human genes including FPR2 (formyl peptide recep tor 2). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 18190720 | 18191939 | Mouse | 49 | description | gene, protein-coding, VALIDATED [RefSeq] |