| 621764 | Foxj1 | forkhead box J1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN cellular response to insulin-like growth factor stimulus; response to 2,3,7,8-tetrachlorodibenzodioxine; response to estradiol; ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 10 | 102065163 | 102069945 | Rat | 194 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 732358 | FOXJ1 | forkhead box J1 | This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymor phisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009] | 17 | 76136333 | 76141245 | Human | 240 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 732359 | Foxj1 | forkhead box J1 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of adaptive immune response based on somatic recombination of immune recep tors built from immunoglobulin superfamily domains; negative regulation of lymphocyte activation; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including cell maturation; determination of left/right symmetry; and establishment of apical/basal cell polarity. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; nose; and respiratory system. Used to study Kartagener syndrome; congenital heart disease; and primary ciliary dyskinesia. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1). [provided by Alliance of Genome Resources, Apr 2025] | 11 | 116221530 | 116226331 | Mouse | 240 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8781097 | Foxj1 | forkhead box J1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN actin cytoskeleton organization ( ortholog); axoneme assembly (ortholog); brain development (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (ortholog) | NW_004955506 | 6127551 | 6132302 | Chinchilla | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11811724 | FOXJ1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred) | 17 | 70084920 | 70089865 | Bonobo | 70 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12333050 | FOXJ1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred) | 9 | 4512898 | 4517764 | Dog | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12437594 | Foxj1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred) | NW_004936594 | 1284799 | 1288898 | Squirrel | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902145 | Foxj1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18397130 | FOXJ1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14215440 | FOXJ1 | forkhead box J1 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN cell maturation (ortholog); cellular response to insulin-like growth factor stimulus (ortholo g); determination of left/right symmetry (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH ammonia | | | | Pig | 70 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251517 | foxj1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626004359 | Foxj1 | forkhead box J1 | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); transcription cis-regulatory region binding (ortholog); INVOLVED IN actin cytoskeleton organization ( ortholog); axoneme assembly (ortholog); brain development (ortholog); ASSOCIATED WITH congenital heart disease (ortholog); genetic disease (ortholog); Kartagener syndrome (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285779137 | foxj1.2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155257908 | foxj1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257029 | foxj1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 288083303 | foxj1.2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286109363 | foxj1.2.S | | | | | | African Clawed Frog | | symbol | gene, null |