| 1315466 | FHOD1 | formin homology 2 domain containing 1 | This gene encodes a protein which is a member of the formin/diaphanous family of proteins. The gene is ubiquitously expressed but is found in abundance in the spleen. The encoded protein has sequence homology to diaphanous and formin proteins within the Formin Homology (FH)1 and FH2 domains. It also contains a coiled-coil domain, a collagen-like domain, two nuclear localization signals, and several potential PKC and PKA phosphorylation sites. It is a predominantly cytoplasmic protein and is expressed in a variety of human cell lines. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] | 16 | 67229389 | 67247481 | Human | 109 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315467 | Fhod1 | formin homology 2 domain containing 1 | Predicted to enable actin filament binding activity and identical protein binding activity. Acts upstream of or within establishment of centrosome localization and nuclear migration. Located in intercalated disc. Is expressed in several structures, including gut; metanephros; nervous system; respira tory system; and sensory organ. Orthologous to human FHOD1 (formin homology 2 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 106055792 | 106074650 | Mouse | 120 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1589776 | Fhod1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); positive regulation of stress fiber assembly (ortholog); FOUND IN cytosol (ortholog); intercalated disc (ortholog); nucleus (ortholog); INTERACTS W ITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 19 | 50116415 | 50135868 | Rat | 110 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9061361 | Fhod1 | formin homology 2 domain containing 1 | INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); positive regulation of stress fiber assembly (ortholog); FOUND IN cytosol (ortholog); intercalated disc (ortholog); nucleus (ortholog) | NW_004955484 | 9380202 | 9396400 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11903821 | FHOD1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); cytosol (inferred) | 16 | 47574949 | 47593022 | Bonobo | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12389281 | FHOD1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); FOUND IN cytoskeleton (inferred); cytosol (inferred); intercalated disc (inferred) | 5 | 82129846 | 82145605 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12489264 | Fhod1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); cytosol (inferred) | NW_004936475 | 17694265 | 17709984 | Squirrel | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625888326 | Fhod1 | formin homology 2 domain containing 1 | INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); positive regulation of stress fiber assembly (ortholog); FOUND IN cytosol (ortholog); intercalated disc (ortholog); nucleus (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18902515 | Fhod1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); positive regulation of stress fiber assembly (ortholog); FOUND IN cytosol (ortholog); intercalated disc (ortholo g); nucleus (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251345 | fhod1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14233956 | FHOD1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); FOUND IN cytoskeleton (inferred); cytosol (inferred); intercalated disc (inferred); INTERACTS WITH graphene oxide | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18375633 | FHOD1 | formin homology 2 domain containing 1 | ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); INVOLVED IN establishment of centrosome localization (ortholog); nuclear migration (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); cytosol (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242969 | fhod1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155233821 | fhod1.S | | | | | | African Clawed Frog | | symbol | gene, null |
