| 1305589 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cocaine | 4 | 126054201 | 126151698 | Rat | 89 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1313708 | FGD5 | FYVE, RhoGEF and PH domain containing 5 | Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 14810688 | 14934571 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1313709 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory o rgan. Orthologous to human FGD5 (FYVE, RhoGEF and PH domain containing 5). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 91955809 | 92052986 | Mouse | 120 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8755491 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN plasma membrane (ortholog) | NW_004955429 | 17297123 | 17367365 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11764563 | FGD5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (in ferred); plasma membrane (inferred) | 3 | 14732712 | 14856251 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12142665 | FGD5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (in ferred); plasma membrane (inferred) | 20 | 4905898 | 5028637 | Dog | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12621462 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (in ferred); plasma membrane (inferred) | NW_004936602 | 432114 | 483964 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14232116 | FGD5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoskeleton (inferred); plasma membra ne (inferred) | | | | Pig | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625942663 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN plasma membrane (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18934682 | Fgd5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN plasma membrane (ortholog) | | | | Naked Mole-Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241543 | fgd5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18477778 | FGD5 | FYVE, RhoGEF and PH domain containing 5 | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); zinc ion binding (inferred); ASSOCIATED WITH Breast Neoplasms (ortholog); Disease Progression (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (in ferred); plasma membrane (inferred) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241542 | fgd5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860885 | fgd5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859180 | fgd5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860828 | fgd5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 628398361 | fgd5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858026 | fgd5.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 5687428 | FGD5-AS1 | FGD5 antisense RNA 1 | ASSOCIATED WITH acute myocardial infarction; INTERACTS WITH beta-lapachone; cyclosporin A; thalidomide | 3 | 14942779 | 14948441 | Human | 8 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 7047808 | FGD5P1 | FYVE, RhoGEF and PH domain containing 5 pseudogene 1 | INTERACTS WITH cadmium dichloride | 3 | 13933056 | 13936944 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
