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11 records found for search term Fgd2
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1309840Fgd2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); phosphatidylinositol phosphate binding (ortholog); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); prostate cancer (ortholog); FOUND2074264077443207Rat83symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1320399FGD2FYVE, RhoGEF and PH domain containing 2The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The enc63700565537029069Human106symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1320400Fgd2FYVE, RhoGEF and PH domain containing 2Enables guanyl-nucleotide exchange factor activity and phosphatidylinositol phosphate binding activity. Acts upstream of or within positive regulation of JUN kinase activity. Located in early endosome; nucleus; and ruffle. Orthologous to human FGD2 (FYVE, RhoGEF172957987829598509Mouse91symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8718756Fgd2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); phosphatidylinositol phosphate binding (ortholog); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); prostate cancer (ortholog); FOUNDNW_00495543760260876038740Chinchilla13symbolgene, protein-coding, MODEL [RefSeq]
12002355FGD2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); pro63656694236591044Bonobo26symbolgene, protein-coding, MODEL [RefSeq]
12412523FGD2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); pro1260692516091972Dog24symbolgene, protein-coding, MODEL [RefSeq]
12541403Fgd2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); proNW_0049364762242385122442795Squirrel24symbolgene, protein-coding, MODEL [RefSeq]
14122869FGD2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); proPig24symbolgene, protein-coding, MODEL [RefSeq]
18708206FGD2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); metal ion binding (inferred); phosphatidylinositol phosphate binding (inferred); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); proGreen Monkey26symbolgene, protein-coding, MODEL [RefSeq]
626053898Fgd2FYVE, RhoGEF and PH domain containing 2ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); phosphatidylinositol phosphate binding (ortholog); INVOLVED IN positive regulation of JUN kinase activity (ortholog); ASSOCIATED WITH COVID-19 (ortholog); ovarian cyst (ortholog); prostate cancer (ortholog); FOUNDBlack Rat12symbolgene, protein-coding, MODEL [RefSeq]
1603024MRAPmelanocortin 2 receptor accessory proteinThis gene encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with213229181332314784Human194old_gene_symbolgene, protein-coding, REVIEWED [RefSeq]