| 620583 | Elovl5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity; INVOLVED IN fatty acid elongation, polyunsaturated fatty acid; very long-chain fatty acid biosynthetic process; fatty acid biosynthetic process (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pa thway; unsaturated fatty acid biosynthetic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendritic tree (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 87671164 | 87737618 | Rat | 218 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1332308 | Elovl5 | ELOVL fatty acid elongase 5 | Enables fatty acid elongase activity. Involved in fatty acid derivative biosynthetic process and fatty acid metabolic process. Is active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory syste m; and sensory organ. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 38. Orthologous to human ELOVL5 (ELOVL fatty acid elongase 5). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 77824647 | 77891801 | Mouse | 248 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1353049 | ELOVL5 | ELOVL fatty acid elongase 5 | This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have bee n associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] | 6 | 53267404 | 53348950 | Human | 240 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8882966 | Elovl5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); fatty acid elongation, monounsaturated fatty acid (ortholog); fatty acid elongation, polyunsaturated fatty acid (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendritic tree (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog) | NW_004955411 | 2747232 | 2812544 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12010027 | ELOVL5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid elongation (inferred); fatty acid elongation, monounsaturated fatty acid (inferred); PARTICIPATES IN alpha-linolenic acid metab olic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendrite (inferred); dendritic tree (inferred); endoplasmic reticulum (inferred) | 6 | 52822038 | 52902122 | Bonobo | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12072958 | ELOVL5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid elongation, monounsaturated fatty acid (inferred); fatty acid elongation, polyunsaturated fatty acid (inferred); PARTICIPATES I N alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendrite (inferred); dendritic tree (inferred); endoplasmic reticulum (inferred) | 12 | 20732641 | 20807748 | Dog | 51 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12491718 | Elovl5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN positive regulation of fatty acid biosynthetic process (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atheroscle rosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendritic tree (ortholog); endoplasmic reticulum membrane (ortholog); neuronal cell body (ortholog) | NW_004936476 | 7536635 | 7618271 | Squirrel | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18607256 | ELOVL5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid elongation (inferred); fatty acid elongation, monounsaturated fatty acid (inferred); PARTICIPATES IN alpha-linolenic acid metab olic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendrite (inferred); dendritic tree (inferred); endoplasmic reticulum (inferred) | | | | Green Monkey | 52 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626160744 | Elovl5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (ortholog); INVOLVED IN fatty acid biosynthetic process (ortholog); fatty acid elongation, monounsaturated fatty acid (ortholog); fatty acid elongation, polyunsaturated fatty acid (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendritic tree (ortholog); endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251935 | elovl5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14153448 | ELOVL5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); fatty acid elongation, monounsaturated fatty acid (inferred); fatty acid elongation, polyunsaturated fatty acid (inferred); PARTICIPATES I N alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atherosclerosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendrite (inferred); dendritic tree (inferred); endoplasmic reticulum (inferred) | | | | Pig | 50 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913804 | Elovl5 | ELOVL fatty acid elongase 5 | ENCODES a protein that exhibits fatty acid elongase activity (inferred); transferase activity (inferred); INVOLVED IN positive regulation of fatty acid biosynthetic process (ortholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; linoleic acid metabolic pathway; ASSOCIATED WITH atheroscle rosis (ortholog); Experimental Liver Cirrhosis (ortholog); genetic disease (ortholog); FOUND IN dendritic tree (ortholog); endoplasmic reticulum membrane (ortholog); neuronal cell body (ortholog) | | | | Naked Mole-Rat | 47 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155258223 | elovl5.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155237297 | elovl5.S | | | | | | African Clawed Frog | | symbol | gene, null |