| 620820 | Eif2b2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity; ATP binding (ortholog); GTP binding (ortholog); INVOLVED IN hippocampus development; positive regulation of axon extension; response to glucose; PARTICIPATES IN translation initiation pathway; RNA transport pathway; ASSOCIAT ED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon; endoplasmic reticulum; eukaryotic translation initiation factor 2B complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 6 | 110597979 | 110604403 | Rat | 146 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 731256 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. [provided by RefSeq, Aug 2011] | 14 | 75002921 | 75012366 | Human | 184 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 731257 | Eif2b2 | eukaryotic translation initiation factor 2B, subunit 2 beta | This gene encodes the beta subunit of eukaryotic initiation factor-2B (EIF2B). EIF2B is involved in protein synthesis and exchanges GDP and GTP for its activation and deactivation. Mutations in the human gene are associated with ovarioleukodystrophy and leukoencephalopathy with vanishing white matte r. [provided by RefSeq, Sep 2015] | 12 | 85266255 | 85273402 | Mouse | 156 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 8713447 | Eif2b2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (ortholog); GTP binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN central nervous system development (ortholog); cytoplasmic translational initiation (ortholog); hippocampus development (ortholog); PARTICIPATES IN trans lation initiation pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog) | NW_004955523 | 553356 | 559376 | Chinchilla | 50 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11760084 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (inferred); GTP binding (inferred); guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN hippocampus development (ortholog); positive regulation of axon extension (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiat ion pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); endoplasmic reticulum (ortholog); eukaryotic translation initiation factor 2B complex (ortholog) | 14 | 55554516 | 55561201 | Bonobo | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12072894 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN hippocampus development (ortholog); positive regulation of axon extension (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (or tholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); endoplasmic reticulum (ortholog); eukaryotic translation initiation factor 2B complex (ortholog) | 8 | 48110521 | 48117175 | Dog | 58 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12450832 | Eif2b2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (inferred); GTP binding (inferred); guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN hippocampus development (ortholog); positive regulation of axon extension (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiat ion pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); endoplasmic reticulum (ortholog); eukaryotic translation initiation factor 2B complex (ortholog) | NW_004936488 | 4150504 | 4156483 | Squirrel | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626052259 | Eif2b2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (ortholog); GTP binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN central nervous system development (ortholog); cytoplasmic translational initiation (ortholog); hippocampus development (ortholog); PARTICIPATES IN trans lation initiation pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog) | | | | Black Rat | 49 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13994825 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN hippocampus development (ortholog); positive regulation of axon extension (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (or tholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); endoplasmic reticulum (ortholog); eukaryotic translation initiation factor 2B complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 59 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231513 | eif2b2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18912396 | Eif2b2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (ortholog); GTP binding (ortholog); guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN cytoplasmic translational initiation (ortholog); hippocampus development (ortholog); myelination (ortholog); PARTICIPATES IN translation initiation pathw ay; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog) | | | | Naked Mole-Rat | 56 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18776488 | EIF2B2 | eukaryotic translation initiation factor 2B subunit beta | ENCODES a protein that exhibits ATP binding (inferred); GTP binding (inferred); guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN hippocampus development (ortholog); positive regulation of axon extension (ortholog); response to glucose (ortholog); PARTICIPATES IN translation initiat ion pathway; ASSOCIATED WITH genetic disease (ortholog); Leukoencephalopathies (ortholog); leukoencephalopathy with vanishing white matter (ortholog); FOUND IN axon (ortholog); endoplasmic reticulum (ortholog); eukaryotic translation initiation factor 2B complex (ortholog) | | | | Green Monkey | 57 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231514 | eif2b2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155251808 | eif2b2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16561778 | AL049780.1 | novel transcript, antisense to EIF2B2 | | | | | Human | | name | gene, lncrna |