| 620389 | Efna2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN axon guidance; olfactory bulb development; bone remodeling (ortholog); PARTICIPATES IN altered ephrin - ephrin receptor bidirectional signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neu romuscular junction; perikaryon; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,4-dihydroxybenzoic acid | 7 | 10167091 | 10177719 | Rat | 100 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1314277 | EFNA2 | ephrin A2 | This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in media ting developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq, Jul 2008] | 19 | 1284227 | 1301431 | Human | 98 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314278 | Efna2 | ephrin A2 | Enables ephrin receptor binding activity. Involved in bone remodeling; ephrin receptor signaling pathway; and osteoclast differentiation. Predicted to be located in neuromuscular junction and perikaryon. Predicted to be active in plasma membrane. Is expressed in several structures, including aliment ary system; central nervous system; ear; genitourinary system; and limb. Orthologous to human EFNA2 (ephrin A2). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 80015316 | 80025844 | Mouse | 116 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8799804 | Efna2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN axon guidance (ortholog); bone remodeling (ortholog); ephrin receptor signaling pathway (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perik aryon (ortholog) | NW_004955495 | 6614828 | 6627287 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12656114 | Efna2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (ortholog); olfactory bulb development (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog) | NW_004936588 | 648336 | 657768 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625907922 | Efna2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN axon guidance (ortholog); bone remodeling (ortholog); ephrin receptor signaling pathway (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perik aryon (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903911 | Efna2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (ortholog); olfactory bulb development (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12026516 | EFNA2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (ortholog); INVOLVED IN axon guidance (ortholog); bone remodeling (ortholog); ephrin receptor signaling pathway (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perik aryon (ortholog) | | | | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232986 | efna2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14029981 | EFNA2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (ortholog); olfactory bulb development (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog) | | | | Pig | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 40908300 | EFNA2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (ortholog); olfactory bulb development (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog) | | | | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18488191 | EFNA2 | ephrin A2 | ENCODES a protein that exhibits ephrin receptor binding (inferred); INVOLVED IN axon guidance (ortholog); olfactory bulb development (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; FOUND IN neuromuscular junction (ortholog); perikaryon (ortholog) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155232987 | efna2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242180 | efna2.S | | | | | | African Clawed Frog | | symbol | gene, null |