| 733013 | Dnase2a | deoxyribonuclease II alpha | Enables deoxyribonuclease II activity. Acts upstream of or within DNA catabolic process; enucleate erythrocyte differentiation; and regulation of immune response. Predicted to be located in lysosome. Is expressed in liver; olfactory epithelium; and vibrissa. Used to study rheumatoid arthritis. Ortho logous to human DNASE2 (deoxyribonuclease 2, lysosomal). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 85635384 | 85638332 | Mouse | 163 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 621457 | Dnase2 | deoxyribonuclease 2, lysosomal | ENCODES a protein that exhibits DNA endonuclease activity; deoxyribonuclease II activity (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); ASSOCIATED WITH AUTOINFLAMMATORY-PANCYTOPENIA SYNDROME (ortholog); Experimental Arthritis (ortholog); rheumatoid arthritis (ortholog); FOUND IN lysoso me (ortholog); INTERACTS WITH (+)-schisandrin B; 1,2,4-trimethylbenzene; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 40149505 | 40152225 | Rat | 132 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1343662 | DNASE2 | deoxyribonuclease 2, lysosomal | This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), th at differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008] | 19 | 12875209 | 12881449 | Human | 158 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 14222868 | DNASE2 | deoxyribonuclease 2, lysosomal | ENCODES a protein that exhibits deoxyribonuclease II activity (ortholog); DNA endonuclease activity (ortholog); INVOLVED IN apoptotic cell clearance (ortholog); ASSOCIATED WITH AUTOINFLAMMATORY-PANCYTOPENIA SYNDROME (ortholog); Experimental Arthritis (ortholog); rheumatoid arthritis (ortholog); FOUN D IN lysosome (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 30 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 10030723 | Gm38426 | predicted gene, 38426 | | 8 | 85639964 | 85649544 | Mouse | | ensembl_gene_symbol | gene, ncrna, VALIDATED [RefSeq] |