| 1307611 | Dmc1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); DNA strand exchange activity (ortholog); identical protein binding (ortholog); INVOLVED IN double-strand break repair involved in meiotic recombination (ortholog); double-strand break repair via homologous recombinatio n (ortholog); gamete generation (ortholog); ASSOCIATED WITH azoospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (ortholog); chromosome, telomeric region (ortholog); condensed nuclear chromosome (ortholog); INTERACTS WITH bisphenol A; formaldehyde; trichloroethene | 7 | 113005278 | 113047854 | Rat | 121 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1316904 | DMC1 | DNA meiotic recombinase 1 | This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] | 22 | 38509147 | 38570183 | Human | 133 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1316905 | Dmc1 | DNA meiotic recombinase 1 | This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. In mouse, deficiency of this gene causes infertility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] | 15 | 79445698 | 79489362 | Mouse | 167 | symbol , old_gene_name , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8989543 | Dmc1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP-dependent activity, acting on DNA (ortholog); DNA strand exchange activity (ortholog); identical protein binding (ortholog); INVOLVED IN double-strand break repair involved in meiotic recombination (ortholog); double-strand break repair via homologous recombinatio n (ortholog); gamete generation (ortholog); ASSOCIATED WITH azoospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (ortholog); chromosome, telomeric region (ortholog); condensed nuclear chromosome (ortholog) | NW_004955413 | 24685311 | 24724269 | Chinchilla | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11895005 | DMC1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH azo ospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (inferred); chromosome, telomeric region (inferred); condensed nuclear chromosome (inferred) | 22 | 19433989 | 19485804 | Bonobo | 64 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12060552 | DMC1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH azo ospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (inferred); chromosome, telomeric region (inferred); condensed nuclear chromosome (inferred) | 10 | 26228662 | 26265377 | Dog | 64 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12456425 | Dmc1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH azo ospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (inferred); chromosome, telomeric region (inferred); condensed nuclear chromosome (inferred) | NW_004936492 | 2754694 | 2788249 | Squirrel | 64 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18916573 | Dmc1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN double-strand break repair involved in meiotic recombination (ortholog); double-strand break repair via homologous recombination (ortholog); gamete generation (ortholog); ASSOCIATED WITH azoospermia (ortholog); CRYPTOZ OOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (ortholog); chromosome, telomeric region (ortholog); lateral element (ortholog) | | | | Naked Mole-Rat | 59 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 288083131 | dmc1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14053670 | DMC1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH azo ospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (inferred); chromosome, telomeric region (inferred); condensed nuclear chromosome (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 65 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14376108 | DMC1 | | | | | | Yeast | | symbol | gene, null |
| 18558955 | DMC1 | DNA meiotic recombinase 1 | ENCODES a protein that exhibits ATP binding (inferred); ATP-dependent activity, acting on DNA (inferred); ATP-dependent DNA damage sensor activity (inferred); INVOLVED IN gamete generation (ortholog); homologous chromosome pairing at meiosis (ortholog); male meiosis I (ortholog); ASSOCIATED WITH azo ospermia (ortholog); CRYPTOZOOSPERMIA (ortholog); primary ovarian insufficiency (ortholog); FOUND IN chromosome (inferred); chromosome, telomeric region (inferred); condensed nuclear chromosome (inferred) | | | | Green Monkey | 64 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 288083132 | dmc1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 1322878 | HID1 | HID1 domain containing | Predicted to act upstream of or within several processes, including insulin processing; secretory granule maturation; and vacuole fusion, non-autophagic. Located in Golgi apparatus; cytoplasmic microtubule; and cytosol. Implicated in developmental and epileptic encephalopathy 105. [provided by Allia nce of Genome Resources, Jul 2025] | 17 | 74950742 | 74972759 | Human | 103 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1604777 | MND1 | meiotic nuclear divisions 1 | The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008] | 4 | 153344649 | 153415118 | Human | 117 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 730859 | PSMC3IP | PSMC3 interacting protein | This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-a ctivate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011] | 17 | 42572310 | 42577831 | Human | 171 | description | gene, protein-coding, REVIEWED [RefSeq] |