| 1318664 | DHX29 | DExH-box helicase 29 | This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells. [provided by RefSeq, Sep 2016] | 5 | 55256055 | 55307694 | Human | 91 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1318665 | Dhx29 | DExH-box helicase 29 | Predicted to enable several functions, including ribonucleoside triphosphate phosphatase activity; ribosomal small subunit binding activity; and translation activator activity. Predicted to be involved in formation of translation preinitiation complex and ribosome assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; connective tissue; genitourinary system; and hemolymphoid system gland. Orthologous to human DHX29 (DExH-box helicase 29). [provided by Alliance of Genome Resources, Apr 2025] | 13 | 113063976 | 113105968 | Mouse | 107 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 2318361 | Dhx29 | DExH-box helicase 29 | ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); ribosomal small subunit binding (ortholog); translation activator activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ribosome assembly (ortholog); PARTICIPATES IN tra nslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosolic small ribosomal subunit (ortholog); eukaryotic 43S preinitiation complex (ortholog); INTERACTS WITH bisphenol A; DDT; gentamycin | 2 | 46293901 | 46344652 | Rat | 96 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9043964 | Dhx29 | DExH-box helicase 29 | ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); ribosomal small subunit binding (ortholog); translation activator activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ribosome assembly (ortholog); PARTICIPATES IN tra nslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosolic small ribosomal subunit (ortholog); eukaryotic 43S preinitiation complex (ortholog) | NW_004955446 | 12362324 | 12412814 | Chinchilla | 9 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11946642 | DHX29 | DExH-box helicase 29 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN formation of translation preinitiation complex (inferred); positive regulation of translation (inferred); positive regulation of translational initiation (inferred); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic 43S preinitiation complex (inferred) | 5 | 58722594 | 58773708 | Bonobo | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12277279 | DHX29 | DExH-box helicase 29 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN formation of translation preinitiation complex (inferred); positive regulation of translational initiation (inferred); ribosome assembly (inferred); PARTICIPATES IN transl ation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic 43S preinitiation complex (inferred) | 2 | 42611630 | 42660328 | Dog | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12583368 | Dhx29 | DExH-box helicase 29 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN formation of translation preinitiation complex (inferred); positive regulation of translational initiation (inferred); ribosome assembly (inferred); PARTICIPATES IN t ranslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic 43S preinitiation complex (inferred) | NW_004936480 | 12458834 | 12504207 | Squirrel | 29 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18507149 | DHX29 | DExH-box helicase 29 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN formation of translation preinitiation complex (inferred); positive regulation of translation (inferred); positive regulation of translational initiation (inferred); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic 43S preinitiation complex (inferred) | | | | Green Monkey | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14241798 | DHX29 | DExH-box helicase 29 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN formation of translation preinitiation complex (inferred); positive regulation of translational initiation (inferred); ribosome assembly (inferred); PARTICIPATES IN t ranslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytoplasm (inferred); cytosolic small ribosomal subunit (inferred); eukaryotic 43S preinitiation complex (inferred) | | | | Pig | 29 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155255396 | dhx29 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626085775 | Dhx29 | DExH-box helicase 29 | ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); ribosomal small subunit binding (ortholog); translation activator activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ribosome assembly (ortholog); PARTICIPATES IN tra nslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosolic small ribosomal subunit (ortholog); eukaryotic 43S preinitiation complex (ortholog) | | | | Black Rat | 9 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18912678 | Dhx29 | DExH-box helicase 29 | ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); ribosomal small subunit binding (ortholog); translation activator activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ribosome assembly (ortholog); PARTICIPATES IN tra nslation initiation pathway; ASSOCIATED WITH prostate cancer (ortholog); FOUND IN cytosolic small ribosomal subunit (ortholog); eukaryotic 43S preinitiation complex (ortholog) | | | | Naked Mole-Rat | 28 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155257978 | dhx29.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 18424560 | LOC103230409 | ATP-dependent RNA helicase DHX29-like | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |
| 625910482 | LOC116887997 | ATP-dependent RNA helicase DHX29-like | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 40918194 | LOC119879306 | ATP-dependent RNA helicase DHX29-like | | | | | Dog | | name | gene, protein-coding, MODEL [RefSeq] |
| 402527992 | LOC134730245 | ATP-dependent RNA helicase DHX29-like | | | | | Bonobo | | name | gene, pseudo, MODEL [RefSeq] |
| 16554905 | AL359976.1 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 (DHX29) pseudogene | | 1 | 189989536 | 189993203 | Human | | name | gene, pseudo, INFERRED [RefSeq] |