Dhx29 (DExH-box helicase 29) - Rat Genome Database

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Gene: Dhx29 (DExH-box helicase 29) Heterocephalus glaber
Analyze
Symbol: Dhx29
Name: DExH-box helicase 29
RGD ID: 18912678
Description: ENCODES a protein that exhibits ribonucleoside triphosphate phosphatase activity (ortholog); ribosomal small subunit binding (ortholog); translation activator activity (ortholog); INVOLVED IN formation of translation preinitiation complex (ortholog); ribosome assembly (ortholog); PARTICIPATES IN translation initiation pathway; ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); prostate cancer (ortholog); FOUND IN cytosolic small ribosomal subunit (ortholog); eukaryotic 43S preinitiation complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent RNA helicase DHX29; DEAH-box helicase 29
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247593,965,685 - 4,013,733 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247593,965,543 - 4,013,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dhx29
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247593,965,685 - 4,013,733 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247593,965,543 - 4,013,600 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DHX29
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38555,256,055 - 55,307,694 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl555,256,055 - 55,307,694 (-)EnsemblGRCh38hg38GRCh38
GRCh37554,551,883 - 54,603,522 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36554,587,830 - 54,639,278 (-)NCBINCBI36Build 36hg18NCBI36
Build 34554,587,830 - 54,639,259NCBI
Celera551,504,864 - 51,556,336 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef551,525,083 - 51,576,484 (-)NCBIHuRef
CHM1_1554,555,919 - 54,607,389 (-)NCBICHM1_1
T2T-CHM13v2.0556,083,337 - 56,135,001 (-)NCBIT2T-CHM13v2.0
Dhx29
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,063,976 - 113,105,968 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,063,988 - 113,105,966 (+)EnsemblGRCm39 Ensembl
GRCm3813112,927,680 - 112,969,432 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13112,927,454 - 112,969,432 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713113,718,001 - 113,759,395 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,048,671 - 114,090,065 (+)NCBIMGSCv36mm8
Celera13117,244,274 - 117,286,508 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
Dhx29
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8246,293,901 - 46,344,652 (+)NCBIGRCr8
mRatBN7.2244,560,653 - 44,611,450 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl244,560,714 - 44,611,445 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0244,787,066 - 44,837,834 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl244,787,002 - 44,837,831 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0263,827,247 - 63,877,717 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4244,306,480 - 44,357,742 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera240,339,409 - 40,384,844 (+)NCBICelera
Cytogenetic Map2q14NCBI
Dhx29
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544612,362,325 - 12,412,963 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544612,362,324 - 12,412,814 (+)NCBIChiLan1.0ChiLan1.0
DHX29
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2458,633,445 - 58,684,515 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1556,787,449 - 56,838,145 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0558,722,594 - 58,773,708 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1560,345,331 - 60,396,244 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl560,345,282 - 60,396,244 (+)Ensemblpanpan1.1panPan2
DHX29
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,611,630 - 42,660,328 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,611,632 - 42,660,207 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,657,379 - 39,706,087 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,075,358 - 43,124,087 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,075,358 - 43,124,020 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1240,153,936 - 40,202,629 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,955,696 - 41,004,412 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,778,709 - 41,824,714 (-)NCBIUU_Cfam_GSD_1.0
Dhx29
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213203,522,300 - 203,567,559 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648012,458,843 - 12,504,202 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648012,458,834 - 12,504,207 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DHX29
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1634,425,708 - 34,478,177 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11634,426,647 - 34,478,233 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21636,535,518 - 36,586,889 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DHX29
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1451,491,356 - 51,543,889 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl451,491,598 - 51,543,774 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666049360,238 - 412,844 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000022046   ⟹   ENSHGLP00000021836
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247593,965,685 - 4,013,733 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000022047   ⟹   ENSHGLP00000021837
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247593,965,685 - 4,013,733 (+)Ensembl
RefSeq Acc Id: XM_004848513   ⟹   XP_004848570
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,965,544 - 4,013,600 (+)NCBI
RefSeq Acc Id: XM_021261416   ⟹   XP_021117075
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,965,544 - 4,013,600 (+)NCBI
RefSeq Acc Id: XM_021261417   ⟹   XP_021117076
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,970,741 - 4,013,600 (+)NCBI
RefSeq Acc Id: XM_021261418   ⟹   XP_021117077
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247593,965,543 - 4,013,600 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004848570 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117075 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117076 (Get FASTA)   NCBI Sequence Viewer  
  XP_021117077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021837
Reference Protein Sequences
RefSeq Acc Id: XP_021117077   ⟸   XM_021261418
- Peptide Label: isoform X4
- UniProtKB: G5C6X0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848570   ⟸   XM_004848513
- Peptide Label: isoform X1
- UniProtKB: G5C6X0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117075   ⟸   XM_021261416
- Peptide Label: isoform X2
- UniProtKB: G5C6X0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117076   ⟸   XM_021261417
- Peptide Label: isoform X3
- UniProtKB: G5C6X0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021837   ⟸   ENSHGLT00000022047
RefSeq Acc Id: ENSHGLP00000021836   ⟸   ENSHGLT00000022046


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015591 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022047 ENTREZGENE
Gene3D-CATH 1.20.120.1080 UniProtKB/TrEMBL
  P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro DEAD-box_helicase_OB_fold UniProtKB/TrEMBL
  DEAD/DEAH_box_helicase_dom UniProtKB/TrEMBL
  DHX29 UniProtKB/TrEMBL
  DNA/RNA_helicase_DEAH_CS UniProtKB/TrEMBL
  HA2_WH UniProtKB/TrEMBL
  Helicase-assoc_dom UniProtKB/TrEMBL
  Helicase_ATP-bd UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Dhx29 ENTREZGENE
PANTHER ATP-DEPENDENT RNA HELICASE UniProtKB/TrEMBL
  ATP-DEPENDENT RNA HELICASE DHX29 UniProtKB/TrEMBL
Pfam DEAD UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HA2_C UniProtKB/TrEMBL
  Helicase_C UniProtKB/TrEMBL
  OB_NTP_bind UniProtKB/TrEMBL
PROSITE DEAH_ATP_HELICASE UniProtKB/TrEMBL
  HELICASE_ATP_BIND_1 UniProtKB/TrEMBL
  HELICASE_CTER UniProtKB/TrEMBL
SMART DEXDc UniProtKB/TrEMBL
  HA2 UniProtKB/TrEMBL
  HELICc UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt G5C6X0 ENTREZGENE, UniProtKB/TrEMBL