| 708480 | Ddx46 | DEAD-box helicase 46 | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); helicase activity (inferred); INVOLVED IN mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN nuclear speck (ortholog); U2-type spliceosomal complex (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene | 17 | 8947237 | 8993705 | Rat | 123 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 734266 | DDX46 | DEAD-box helicase 46 | This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation , nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2014] | 5 | 134758779 | 134831121 | Human | 126 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 734267 | Ddx46 | DEAD box helicase 46 | Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in U2-type prespliceosome assembly. Predicted to be located in fibrillar center and nuclear speck. Predicted to be part of U2-type spliceosomal complex. Predicted to be active in nucleus. Is expressed in cerebral cortex ventricular layer. Orthologous to human DDX46 (DEAD-box helicase 46). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 55782790 | 55829080 | Mouse | 141 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9062004 | Ddx46 | DEAD-box helicase 46 | INVOLVED IN mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN nuclear speck (ortholog); U2-type spliceosomal complex (ortholog) | NW_004955408 | 29981509 | 30031473 | Chinchilla | 6 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11846123 | DDX46 | DEAD-box helicase 46 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN U2-type spliceosomal complex (ortholog) | 5 | 130185793 | 130232208 | Bonobo | 20 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12335731 | DDX46 | DEAD-box helicase 46 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN U2-type spliceosomal complex (ortholog) | 11 | 22834843 | 22906976 | Dog | 22 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 626060536 | Ddx46 | DEAD-box helicase 46 | INVOLVED IN mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN nuclear speck (ortholog); U2-type spliceosomal complex (ortholog) | | | | Black Rat | 6 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18925448 | Ddx46 | DEAD-box helicase 46 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN U2-type spliceosomal complex (ortholog) | | | | Naked Mole-Rat | 19 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155249867 | ddx46 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18367083 | DDX46 | DEAD-box helicase 46 | INVOLVED IN mRNA splicing, via spliceosome (ortholog); U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN nuclear speck (ortholog); U2-type spliceosomal complex (ortholog) | | | | Green Monkey | 6 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14040177 | DDX46 | DEAD-box helicase 46 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN U2-type prespliceosome assembly (ortholog); PARTICIPATES IN spliceosome pathway; FOUND IN U2-type spliceosomal complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 23 | symbol , old_gene_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 155255947 | ddx46.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12576125 | LOC101956200 | probable ATP-dependent RNA helicase DDX46 | ENCODES a protein that exhibits ATP binding (inferred); helicase activity (inferred); hydrolase activity (inferred); INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); FOUND IN Cajal body (inferred); nuclear speck (inferred); spliceosomal comp lex (inferred) | NW_004936597 | 2007910 | 2039739 | Squirrel | 16 | old_gene_name , name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 12641214 | LOC106145123 | probable ATP-dependent RNA helicase DDX46 | | NW_004936597 | 1993702 | 1997854 | Squirrel | | old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 40902442 | LOC119627888 | probable ATP-dependent RNA helicase DDX46 | | | | | Green Monkey | | name | gene, protein-coding, MODEL [RefSeq] |
| 40898707 | LOC119623256 | probable ATP-dependent RNA helicase DDX46 pseudogene | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |