| 71092 | Csrp3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding; RNA polymerase II-specific DNA-binding transcription factor binding; actinin binding (ortholog); INVOLVED IN blood vessel remodeling; positive regulation of myotube differentiation; positive regulation of transcription by RNA polymerase II; ASSOCIATED WIT H Right Ventricular Hypertrophy; Animal Disease Models (ortholog); cardiomyopathy (ortholog); FOUND IN cytoplasm; nucleus; Z disc; INTERACTS WITH 1-benzylpiperazine; 2,3,7,8-tetrachlorodibenzodioxine; 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile | 1 | 107664338 | 107682916 | Rat | 240 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733068 | CSRP3 | cysteine and glycine rich protein 3 | This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulatio n, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008] | 11 | 19182030 | 19201983 | Human | 450 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733069 | Csrp3 | cysteine and glycine-rich protein 3 | Enables actinin binding activity and telethonin binding activity. A structural constituent of muscle. Involved in several processes, including cardiac muscle contraction; cardiac myofibril assembly; and detection of muscle stretch. Acts upstream of or within several processes, including T-tubule org anization; insulin receptor signaling pathway; and muscle cell cellular homeostasis. Located in Z disc. Is expressed in several structures, including genitourinary system; great vessel of heart; heart; limb segment; and skeletal musculature. Used to study congestive heart failure; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Human ortholog(s) of this gene implicated in dilated cardiomyopathy; dilated cardiomyopathy 1M; hypertrophic cardiomyopathy; and hypertrophic cardiomyopathy 12. Orthologous to human CSRP3 (cysteine and glycine rich protein 3). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 48480146 | 48497799 | Mouse | 275 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8742720 | Csrp3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits actinin binding (ortholog); identical protein binding (ortholog); MRF binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle contraction (ortholog); cardiac muscle hypertrophy (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); ca rdiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | NW_004955476 | 155913 | 176122 | Chinchilla | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11714340 | CSRP3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | 11 | 19208025 | 19228000 | Bonobo | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12381547 | CSRP3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (ortholog) | 21 | 41300277 | 41318788 | Dog | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12707554 | Csrp3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | NW_004936654 | 271067 | 313251 | Squirrel | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625938538 | Csrp3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits actinin binding (ortholog); identical protein binding (ortholog); MRF binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle contraction (ortholog); cardiac muscle hypertrophy (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); ca rdiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | | | | Black Rat | 73 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14087326 | CSRP3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (ortholog) | | | | Pig | 80 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18911215 | Csrp3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155250394 | csrp3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18451607 | CSRP3 | cysteine and glycine rich protein 3 | ENCODES a protein that exhibits MRF binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); cardiac muscle tissue development (ortholog); glucose homeostasis (ortholog); ASSOCIATED WITH Animal Disease Models (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Green Monkey | 80 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255859 | csrp3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 14392686 | CSRP3-AS1 | CSRP3 and E2F8 antisense RNA 1 | ASSOCIATED WITH cardiomyopathy; INTERACTS WITH dimethylselenide; hydroxyl; ozone | 11 | 19196713 | 19313258 | Human | 4 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1352848 | CSRP2 | cysteine and glycine rich protein 2 | CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activ ity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] | 12 | 76858709 | 76879019 | Human | 204 | description | gene, protein-coding, REVIEWED [RefSeq] |