| 1304883 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); ATP-dependent peptidase activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); proteolysis (ortholog); proteolysis involved in protein catabolic process (ortholog); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (ortholog); mitochondrial endopeptidase Clp complex (ortholog); mitochondrial matrix (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 74700602 | 74740244 | Rat | 164 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312578 | CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit X | The protein encoded by this gene is part of a protease found in mitochondria. This protease is ATP-dependent and targets specific proteins for degradation. The protease consists of two heptameric rings of the CLPP catalytic subunit sandwiched between two hexameric rings of the chaperone subunit enco ded by this gene. Targeted proteins are unwound by this protein and then passed on to the CLPP subunit for degradation. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015] | 15 | 65148219 | 65185342 | Human | 157 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312579 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit | Enables ATP binding activity and ATP hydrolysis activity. Predicted to be involved in ATP metabolic process and proteolysis involved in protein catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system. Human ortholog(s) of this gene implicated in erythropoietic protoporphyria. Orthologous to human CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 65201533 | 65237940 | Mouse | 175 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8916597 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); ATP-dependent peptidase activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); proteolysis (ortholog); proteolysis involved in protein catabolic process (ortholog); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (ortholog); mitochondrial endopeptidase Clp complex (ortholog); mitochondrial matrix (ortholog) | NW_004955450 | 10256124 | 10289832 | Chinchilla | 21 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 11852968 | CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN ATP metabolic process (inferred); protein folding (inferred); proteolysis (inferred); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (inferred); mitochondrial endopeptidase Clp complex (inferred); mitochondrial matrix (inferred) | 15 | 44088070 | 44128730 | Bonobo | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12265014 | CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN ATP metabolic process (inferred); proteolysis (inferred); proteolysis involved in protein catabolic process (inferred); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (inferred); mitochondrial endopeptidase Clp complex (inferred); mitochondrial matrix (inferred) | 30 | 29515907 | 29560318 | Dog | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12709798 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN ATP metabolic process (inferred); protein folding (inferred); proteolysis (inferred); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (inferred); mitochondrial endopeptidase Clp complex (inferred); mitochondrial matrix (inferred) | NW_004936471 | 25447750 | 25484956 | Squirrel | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18405451 | CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN ATP metabolic process (inferred); protein folding (inferred); proteolysis (inferred); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (inferred); mitochondrial endopeptidase Clp complex (inferred); mitochondrial matrix (inferred) | | | | Green Monkey | 37 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18907641 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP-dependent peptidase activity (ortholog); peptidase activator activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (ortholog); mitochondrial endopeptidase C lp complex (ortholog) | | | | Naked Mole-Rat | 30 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 625941890 | Clpx | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); ATP-dependent peptidase activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); proteolysis (ortholog); proteolysis involved in protein catabolic process (ortholog); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (ortholog); mitochondrial endopeptidase Clp complex (ortholog); mitochondrial matrix (ortholog) | | | | Black Rat | 21 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 14179047 | CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit X | ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent peptidase activity (inferred); INVOLVED IN ATP metabolic process (inferred); protein folding (inferred); proteolysis (inferred); ASSOCIATED WITH Erythropoietic Protoporphyria 2 (ortholog); FOUND IN endopeptidase Clp complex (inferred); mitochondrial endopeptidase Clp complex (inferred); mitochondrial matrix (inferred) | | | | Pig | 35 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 155253871 | clpx | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155236412 | clpx.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155243576 | clpx.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16552277 | Z98755.1 | ClpX caseinolytic protease X homolog (E. coli) (CLPX) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16565535 | AC064872.1 | ClpX caseinolytic peptidase X homolog (E. coli) (CLPX) pseudogene | | 2 | 78437864 | 78438916 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 16552782 | BX842559.1 | ClpX caseinolytic peptidase X homolog (E. coli) (CLPX) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 18669475 | LOC103234897 | ATP-dependent clpX-like chaperone, mitochondrial | | | | | Green Monkey | | old_gene_name , name | gene, pseudo, MODEL [RefSeq] |