| 1303043 | Clic1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (ortholog); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); E xperimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial membrane; cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 20 | 3769522 | 3778367 | Rat | 188 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1353337 | CLIC1 | chloride intracellular channel 1 | Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 famil y; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008] | 6 | 31730581 | 31737318 | Human | 191 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1623030 | Clic1 | chloride intracellular channel 1 | Predicted to enable chloride channel activity. Acts upstream of or within positive regulation of osteoblast differentiation and regulation of mitochondrial membrane potential. Located in mitochondrion and nucleus. Is expressed in brain; early conceptus; and heart valve. Orthologous to human CLIC1 yle='font-weight:700;'>CLIC1 (chloride intracellular channel 1). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 35269219 | 35277695 | Mouse | 191 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8791544 | Clic1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (ortholog); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); E xperimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular exosome (ortholog) | NW_004955437 | 269276 | 275949 | Chinchilla | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12002394 | CLIC1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog ); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial membrane (ortholog); mitochondrion (ortholog); nucleus (ortholog) | 6 | 31391958 | 31397920 | Bonobo | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12366438 | CLIC1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog ); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog); extracellular exosome (ortholog); mitochondrial membrane (ortholog) | 12 | 1209777 | 1215229 | Dog | 45 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12633639 | Clic1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog ); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial membrane (ortholog) | NW_004936727 | 1797966 | 1803401 | Squirrel | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18909349 | Clic1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog ); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog); extracellular exosome (ortholog); mitochondrial membrane (ortholog) | | | | Naked Mole-Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18770645 | CLIC1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog ); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN mitochondrial membrane (ortholog) | | | | Green Monkey | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14072733 | CLIC1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squa mous cell carcinoma (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN cytosol (ortholog); extracellular exosome (ortholog); nuclear envelope (ortholog) | | | | Pig | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626102870 | Clic1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (ortholog); INVOLVED IN chloride transport (ortholog); platelet aggregation (ortholog); positive regulation of osteoblast differentiation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); esophagus squamous cell carcinoma (ortholog); E xperimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular exosome (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14190786 | CLIC1 | chloride intracellular channel 1 | ENCODES a protein that exhibits chloride channel activity (inferred); glutathione dehydrogenase (ascorbate) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN positive regulation of osteoblast differentiation (ortholog); regulation of mitochondrial membrane potential (ortholog); FO UND IN mitochondrial membrane (ortholog); mitochondrion (ortholog) | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235452 | clic1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155243199 | clic1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239996 | clic1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38662211 | CLIC1P2 | CLIC1 pseudogene 2 | | 17 | 65642960 | 65644230 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 38666552 | CLIC1P3 | CLIC1 pseudogene 3 | | 16 | 86434844 | 86435498 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16564978 | AC092327.1 | chloride intracellular channel 1 (CLIC1) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 5508856 | CLIC1P1 | chloride intracellular channel 1 pseudogene 1 | | 12 | 120914392 | 120915323 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 735803 | CLIC6 | chloride intracellular channel 6 | This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2015] | 21 | 34668994 | 34718223 | Human | 107 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735804 | Clic6 | chloride intracellular channel 6 | Predicted to enable chloride channel activity; dopamine receptor binding activity; and identical protein binding activity. Predicted to be involved in chloride transmembrane transport. Predicted to be located in cytoplasm and plasma membrane. Predicted to be part of chloride channel complex. Is expr essed in several structures, including cardiovascular system; central nervous system; gut; sensory organ; and urinary system. Orthologous to human CLIC6 (chloride intracellular channel 6). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 92295035 | 92338129 | Mouse | 115 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |