| 1308027 | Cldn10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); regulation of monoatomic ion transport (ortholog); PARTICIPATES IN hepatitis C pathway; ASSOCIATED WITH genetic disease (ortho log); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN bicellular tight junction (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog); INTERACTS WITH 17beta-estradiol 3-benzoate; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine | 15 | 102269858 | 102361589 | Rat | 122 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1317558 | CLDN10 | claudin 10 | This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cel l sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010] | 13 | 95433755 | 95579759 | Human | 131 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1317559 | Cldn10 | claudin 10 | This intronless gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight unction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endot helial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Six alternatively spliced transcript variants have been identified, which encode different isoforms with distinct electric charge of the first extracellular loop and with or without the fourth transmembrane region. These isoforms exhibit distinct localization and function in paracellular anion or cation permeability. [provided by RefSeq, Aug 2010] | 14 | 119025283 | 119111937 | Mouse | 131 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 9005810 | Cldn10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); regulation of monoatomic ion transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypo kalemia (ortholog); FOUND IN bicellular tight junction (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog) | NW_004955404 | 14483217 | 14597912 | Chinchilla | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11923660 | CLDN10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog) | 13 | 76728572 | 76755685 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12374840 | CLDN10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN regulation of monoatomic ion transport (inferred); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog) | 22 | 46098671 | 46225239 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12631582 | Cldn10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog) | NW_004936472 | 14205311 | 14308932 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13849560 | CLDN10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN regulation of monoatomic ion transport (inferred); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog); IN TERACTS WITH deoxynivalenol | | | | Pig | 27 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 287732233 | cldn10 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625871844 | Cldn10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); regulation of monoatomic ion transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypo kalemia (ortholog); FOUND IN bicellular tight junction (ortholog); cytoplasm (ortholog); endoplasmic reticulum (ortholog) | | | | Black Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18918620 | Cldn10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog) | | | | Naked Mole-Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18576014 | CLDN10 | claudin 10 | ENCODES a protein that exhibits identical protein binding (ortholog); paracellular tight junction channel activity (ortholog); INVOLVED IN paracellular transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); HELIX syndrome (ortholog); hypokalemia (ortholog); FOUND IN endoplasmic reticulum (ortholog); tight junction (ortholog) | | | | Green Monkey | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 287731823 | cldn10.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 6481149 | CLDN10-AS1 | CLDN10 antisense RNA 1 | | 13 | 95479444 | 95533910 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |