Chkb Gene Search Result

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17 records found for search term Chkb

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
61826	Chkb	choline kinase beta	ENCODES a protein that exhibits choline kinase activity; ethanolamine kinase activity (ortholog); INVOLVED IN muscle organ development (ortholog); phosphatidylcholine biosynthetic process (ortholog); phosphatidylethanolamine biosynthetic process (ortholog); PARTICIPATES IN glycerophospholipid metabo ... (more) lic pathway; ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dystrophy (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide	7	122380592	122385102	Rat	112	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
62117	Chkb	choline kinase beta	Enables choline kinase activity. Acts upstream of or within muscle organ development and phosphatidylcholine biosynthetic process. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; cranium; heart; and sensory organ. Used to ... (more) study megaconial type congenital muscular dystrophy. Human ortholog(s) of this gene implicated in intellectual disability; megaconial type congenital muscular dystrophy; muscular dystrophy; narcolepsy; and recurrent hypersomnia. Orthologous to human CHKB (choline kinase beta). [provided by Alliance of Genome Resources, Jul 2025]	15	89310552	89314130	Mouse	129	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1604071	CHKB	choline kinase beta	Choline kinase (CK) and ethanolamine kinase (EK) catalyze the phosphorylation of choline/ethanolamine to phosphocholine/phosphoethanolamine. This is the first enzyme in the biosynthesis of phosphatidylcholine/phosphatidylethanolamine in all animal cells. The highly purified CKs from mammalian source ... (more) s and their recombinant gene products have been shown to have EK activity also, indicating that both activities reside on the same protein. The choline kinase-like protein encoded by CHKL belongs to the choline/ethanolamine kinase family; however, its exact function is not known. Read-through transcripts are expressed from this locus that include exons from the downstream CPT1B locus. [provided by RefSeq, Jun 2009]	22	50578963	50582849	Human	135	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
9002953	Chkb	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); ethanolamine kinase activity (ortholog); INVOLVED IN phosphatidylethanolamine biosynthetic process (ortholog); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dy ... (more) strophy (ortholog)	NW_004955413	33588375	33592054	Chinchilla	11	symbol	gene, protein-coding, MODEL [RefSeq]
11725506	CHKB	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN CDP-choline pathway (inferred); lipid metabolic process (inferred); phosphatidylcholine biosynthetic process (inferred); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy ( ... (more) ortholog); muscular dystrophy (ortholog); FOUND IN cytoplasm (inferred)	22	30825128	30829203	Bonobo	28	symbol	gene, protein-coding, MODEL [RefSeq]
12111096	CHKB	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN CDP-choline pathway (inferred); lipid metabolic process (inferred); phospholipid biosynthetic process (inferred); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholo ... (more) g); muscular dystrophy (ortholog)	10	16733071	16736797	Dog	23	symbol	gene, protein-coding, MODEL [RefSeq]
12486663	Chkb	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN CDP-choline pathway (inferred); lipid metabolic process (inferred); phosphatidylcholine biosynthetic process (inferred); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy ( ... (more) ortholog); muscular dystrophy (ortholog); FOUND IN cytoplasm (inferred)	NW_004936629	242876	246806	Squirrel	26	symbol	gene, protein-coding, MODEL [RefSeq]
14268330	CHKB	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN muscle organ development (ortholog); phosphatidylcholine biosynthetic process (ortholog); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dystrophy ( ... (more) ortholog)				Pig	30	symbol	gene, protein-coding, PROVISIONAL [RefSeq]
18629628	CHKB	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN muscle organ development (ortholog); phosphatidylcholine biosynthetic process (ortholog); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dystrophy ( ... (more) ortholog); FOUND IN cytoplasm (inferred)				Green Monkey	31	symbol	gene, protein-coding, MODEL [RefSeq]
284422876	chkb						Tropical Clawed Frog		symbol	gene, null
18921427	Chkb	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); INVOLVED IN muscle organ development (ortholog); phosphatidylcholine biosynthetic process (ortholog); ASSOCIATED WITH intellectual disability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dystrophy ( ... (more) ortholog); FOUND IN cytoplasm (inferred)				Naked Mole-Rat	29	symbol	gene, protein-coding, MODEL [RefSeq]
625838401	Chkb	choline kinase beta	ENCODES a protein that exhibits choline kinase activity (ortholog); ethanolamine kinase activity (ortholog); INVOLVED IN muscle organ development (ortholog); phosphatidylcholine biosynthetic process (ortholog); phosphatidylethanolamine biosynthetic process (ortholog); ASSOCIATED WITH intellectual di ... (more) sability (ortholog); megaconial type congenital muscular dystrophy (ortholog); muscular dystrophy (ortholog)				Black Rat	15	symbol	gene, protein-coding, MODEL [RefSeq]
287202816	chkb.L						African Clawed Frog		symbol	gene, null
284814364	chkb.S						African Clawed Frog		symbol	gene, null
7254767	CHKB-DT	CHKB divergent transcript	INTERACTS WITH aflatoxin B1; cisplatin; methotrexate	22	50583026	50595281	Human	4	symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
5132985	CHKB-CPT1B	CHKB-CPT1B readthrough (NMD candidate)	The genes CHKB and CPT1B are adjacent on chromosome 22 and read-through transcripts are expressed that include exons from both loci. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to express proteins. [provide ... (more) d by RefSeq, Jun 2009]	22	50568861	50582999	Human	8	symbol , COSMIC , name , description , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
2313193	Gm44502	predicted readthrough transcript (NMD candidate), 44502	This locus represents naturally occurring read-through transcription between the neighboring choline kinase beta (Chkb) and carnitine palmitoyltransferase 1b, muscle (Cpt1b) genes. Similar read-through transcription has also been identified between the homologou ... (more) s genes in human and rat. These read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to produce a protein; the functional significance of these transcripts has yet to be determined. [provided by RefSeq, Nov 2010]	15	89300608	89314130	Mouse		old_gene_name , description , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]