| 1549745 | Cdyl | chromodomain Y-like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (ortholog); chromatin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); random inactivation of X chromosome (ortholog); spermatid dev elopment (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (ortholog); cytoplasm (ortholog); nuclear speck (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 17 | 29188697 | 29409805 | Rat | 137 | symbol , old_gene_name , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1556912 | Cdyl | chromodomain protein, Y chromosome-like | Enables chromatin binding activity. Involved in negative regulation of peptidyl-lysine crotonylation; random inactivation of X chromosome; and spermatid development. Located in chromosome; cytoplasm; and nucleus. Is expressed in 2-cell stage embryo; 4-cell stage embryo; cap mesenchyme; and ureteric tip. Used to study epilepsy. Orthologous to human CDYL (chromodomain Y like). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 35843801 | 36058047 | Mouse | 127 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606325 | CDYL | chromodomain Y like | Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] | 6 | 4706138 | 4955544 | Human | 120 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 8931103 | Cdyl | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (ortholog); chromatin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); random inactivation of X chromosome (ortholog); spermatid dev elopment (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (ortholog); cytoplasm (ortholog); nuclear speck (ortholog) | NW_004955465 | 8570197 | 8780551 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12024398 | CDYL | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (inferred); chromatin binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinom a (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); nuclear speck (inferred) | 6 | 4607088 | 4790742 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12281794 | CDYL | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (inferred); chromatin binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (inferred); random inactivation of X chromosome (inferred); spermatid devel opment (inferred); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); nuclear speck (inferred); INTERACTS WITH bisphenol A | 35 | 4844757 | 5074967 | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12651897 | Cdyl | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (inferred); chromatin binding (inferred); lyase activity (inferred); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN c hromosome (inferred); cytoplasm (inferred); nuclear speck (inferred) | NW_004936534 | 7525618 | 7601184 | Squirrel | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14023869 | CDYL | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (inferred); chromatin binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN negative regulation of DNA-templated transcription (inferred); random inactivation of X chromosome (inferred); spermatid devel opment (inferred); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); nuclear speck (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18736622 | CDYL | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (inferred); chromatin binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinom a (ortholog); FOUND IN chromosome (inferred); cytoplasm (inferred); nuclear speck (inferred) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921569 | Cdyl | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (ortholog); chromatin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); random inactivation of X chromosome (ortholog); spermatid dev elopment (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (ortholog); cytoplasm (ortholog); nuclear speck (ortholog) | | | | Naked Mole-Rat | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284353072 | cdyl | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626078890 | Cdyl | chromodomain Y like | ENCODES a protein that exhibits (2E)-butenoyl-CoA hydratase activity (ortholog); chromatin binding (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN negative regulation of peptidyl-lysine crotonylation (ortholog); random inactivation of X chromosome (ortholog); spermatid dev elopment (ortholog); ASSOCIATED WITH epilepsy (ortholog); lung small cell carcinoma (ortholog); FOUND IN chromosome (ortholog); cytoplasm (ortholog); nuclear speck (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 287814299 | cdyl.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286623963 | cdyl.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 14700599 | CDYL-AS1 | CDYL antisense RNA 1 | | 6 | 4774526 | 4775426 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 11571532 | CDYLP1 | CDYL pseudogene 1 | INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 4,4'-sulfonyldiphenol; bisphenol A | 3 | 16692748 | 16693432 | Human | 5 | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16570562 | AL356747.1 | novel transcript, antisense to CDYL | | | | | Human | | name | gene, lncrna |
| 16555238 | AC073488.1 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570038 | AC073488.10 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570041 | AC073488.11 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16569981 | AC073488.2 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16569982 | AC073488.3 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570006 | AC073488.4 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570010 | AC073488.5 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570011 | AC073488.6 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570013 | AC073488.7 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570017 | AC073488.8 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16570030 | AC073488.9 | chromodomain protein, Y chromosome-like (CDYL) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 1309548 | Cdyl2 | chromodomain Y-like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (ortholog); histone H3K9me2/3 reader activity (ortholog); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradio l; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 19 | 61500702 | 61691746 | Rat | 71 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1319946 | CDYL2 | chromodomain Y like 2 | Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025] | 16 | 80597907 | 80805037 | Human | 69 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1319947 | Cdyl2 | chromodomain protein, Y chromosome-like 2 | Enables methylated histone binding activity. Located in nucleus. Orthologous to human CDYL2 (chromodomain Y like 2). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 117295462 | 117459730 | Mouse | 74 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8845424 | Cdyl2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (ortholog); histone H3K9me2/3 reader activity (ortholog); FOUND IN nucleus (ortholog) | NW_004955522 | 3403542 | 3458029 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11814151 | CDYL2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (inferred); histone H3K9me2/3 reader activity (inferred); transcription corepressor activity (inferred); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (in ferred) | 16 | 61196716 | 61409662 | Bonobo | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12294590 | CDYL2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (inferred); histone H3K9me2/3 reader activity (inferred); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred) | 5 | 71080757 | 71133585 | Dog | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12688802 | Cdyl2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (inferred); histone H3K9me2/3 reader activity (inferred); transcription corepressor activity (inferred); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (in ferred) | NW_004936475 | 28333471 | 28386643 | Squirrel | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14168201 | CDYL2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (inferred); histone H3K9me2/3 reader activity (inferred); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred) | | | | Pig | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18711050 | CDYL2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (inferred); histone H3K9me2/3 reader activity (inferred); transcription corepressor activity (inferred); INVOLVED IN chromatin organization (inferred); negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (in ferred) | | | | Green Monkey | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18933050 | Cdyl2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (ortholog); histone H3K9me2/3 reader activity (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (inferred); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284635905 | cdyl2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625969493 | Cdyl2 | chromodomain Y like 2 | ENCODES a protein that exhibits histone H3K27me3 reader activity (ortholog); histone H3K9me2/3 reader activity (ortholog); FOUND IN nucleus (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284614560 | cdyl2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 284555587 | cdyl2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16562829 | AC099313.1 | novel transcript, antisense to CDYL2 | | | | | Human | | name | gene, lncrna |
| 16562557 | AC092332.1 | novel transcript, sense intronic to CDYL2 | | | | | Human | | name | gene, lncrna |