| 619874 | Cdkl3 | cyclin-dependent kinase-like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension; negative regulation of axon extension; positive regulation of dendrite morphogenesis; FOUND IN cytoplasm; nucleus; INTERACTS WITH 1,3,5-trinitro-1,3,5-triazinane; 2,4-dinitrotoluene; acetamide | 10 | 36755413 | 36850197 | Rat | 81 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731372 | CDKL3 | cyclin dependent kinase like 3 | The protein encoded by this gene is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This gen e was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] | 5 | 134283345 | 134371624 | Human | 86 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 731373 | Cdkl3 | cyclin dependent kinase like 3 | Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within dendrite extension; negative regulation of axon extension; and positive regulation of dendrite morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several stru ctures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human CDKL3 (cyclin dependent kinase like 3). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 51891694 | 51980605 | Mouse | 81 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8861586 | Cdkl3 | cyclin dependent kinase like 3 | INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (ortholog) | NW_004955408 | 5466943 | 5552572 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11881393 | CDKL3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (orthol og); FOUND IN cytoplasm (inferred); nucleus (inferred) | 5 | 129701972 | 129774627 | Bonobo | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12176315 | CDKL3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); hydrolase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (ort holog); FOUND IN chromosome, centromeric region (inferred); cytoplasm (inferred); spindle pole (inferred) | 11 | 22416098 | 22524629 | Dog | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12444080 | Cdkl3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (orthol og); FOUND IN cytoplasm (inferred); nucleus (inferred) | NW_004936647 | 914057 | 961953 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929389 | Cdkl3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (orthol og); FOUND IN caveola (inferred); early endosome (inferred); focal adhesion (inferred) | | | | Naked Mole-Rat | 38 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626166652 | Cdkl3 | cyclin dependent kinase like 3 | INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13996197 | CDKL3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (orthol og); FOUND IN cytoplasm (inferred) | | | | Pig | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18757722 | CDKL3 | cyclin dependent kinase like 3 | ENCODES a protein that exhibits ATP binding (inferred); cyclin-dependent protein serine/threonine kinase activity (inferred); kinase activity (inferred); INVOLVED IN dendrite extension (ortholog); negative regulation of axon extension (ortholog); positive regulation of dendrite morphogenesis (orthol og); FOUND IN cytoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |