| 621406 | Cdc42bpa | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits ATP binding; identical protein binding; magnesium ion binding; INVOLVED IN actin cytoskeleton organization; actomyosin structure organization; cell migration; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN actomyosin; cell leading edge; cell-cell junction; INTERACTS WI TH 1,1-dichloroethene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 13 | 94215359 | 94435681 | Rat | 161 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733007 | Cdc42bpa | CDC42 binding protein kinase alpha | Predicted to enable several functions, including ATP binding activity; identical protein binding activity; and magnesium ion binding activity. Acts upstream of or within microtubule cytoskeleton organization and nuclear migration. Located in lamellipodium. Is expressed in cerebellum. Orthologous to human CDC42BPA (CDC42 binding protein kinase alpha). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 179787058 | 179993171 | Mouse | 153 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1351605 | CDC42BPA | CDC42 binding protein kinase alpha | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain , and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2018] | 1 | 226989858 | 227318492 | Human | 150 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8852754 | Cdc42bpa | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actomyosin structure organization (ortholog); cell migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN actomyosin (ortholog); cell leading edge (ortholog); cell-cell junction (ortholog) | NW_004955406 | 9906195 | 10178281 | Chinchilla | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11797767 | CDC42BPA | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); nuclear migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog) | 1 | 202448571 | 202780486 | Bonobo | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12144269 | CDC42BPA | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); nuclear migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog) | 7 | 37775133 | 38084136 | Dog | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12608752 | Cdc42bpa | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); nuclear migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog) | NW_004936526 | 3686403 | 3996035 | Squirrel | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18556347 | CDC42BPA | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); nuclear migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog) | | | | Green Monkey | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625920001 | Cdc42bpa | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); magnesium ion binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actomyosin structure organization (ortholog); cell migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN actomyosin (ortholog); cell leading edge (ortholog); cell-cell junction (ortholog) | | | | Black Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18908419 | Cdc42bpa | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits identical protein binding (ortholog); magnesium ion binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); cell migration (ortholog); cytoskeleton organization (ortholog); ASSOCIATED WITH COVID- 19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog) | | | | Naked Mole-Rat | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155251987 | cdc42bpa | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13963339 | CDC42BPA | CDC42 binding protein kinase alpha | ENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN cytoskeleton organization (ortholog); microtubule cytoskeleton organization (ortholog); nuclear migration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cell leading edge (ortholog); cell-cell junction (ortholog); INTERACTS WITH resveratrol | | | | Pig | 46 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242410 | cdc42bpa.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155251889 | cdc42bpa.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16572616 | AL353689.3 | novel transcript, antisense to CDC42BPA | | | | | Human | | name | gene, lncrna |
| 16572609 | AL627308.3 | novel transcript, antisense to CDC42BPA | | | | | Human | | name | gene, lncrna |
