| 620864 | Ccnl1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (ortholog); INVOLVED IN regulation of mRNA splicing, via spliceosome (ortholog); regulation of RNA splicing (ortholog); FOUND IN nuclear speck; cyclin L-CDK11 complex (ortholog); nuclear body (ortholo g); INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 152495169 | 152508855 | Rat | 172 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733406 | CCNL1 | cyclin L1 | Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Involved in regulation of RNA splicing. Located in nucleus. Part of cyclin-dependent protein kinase holoenzyme complex. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 157143121 | 157160147 | Human | 172 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 733407 | Ccnl1 | cyclin L1 | Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of RNA splicing. Predicted to be located in nuclear speck. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex and transcription elongation factor co mplex. Predicted to be active in nucleus. Is expressed in head. Orthologous to human CCNL1 (cyclin L1). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 65853333 | 65869451 | Mouse | 171 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8770648 | Ccnl1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (ortholog); INVOLVED IN regulation of mRNA splicing, via spliceosome (ortholog); regulation of RNA splicing (ortholog); FOUND IN cyclin L-CDK11 complex (ortholog); nuclear body (ortholog); nuclear spe ck (ortholog) | NW_004955448 | 8112774 | 8125912 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11874159 | CCNL1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN nuclear speck (ortholog) | 3 | 154192971 | 154210468 | Bonobo | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12562590 | Ccnl1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN nuclear speck (ortholog) | NW_004936519 | 4044762 | 4056987 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13389977 | CCNL1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN nuclear speck (ortholog) | 23 | 50639851 | 50643777 | Dog | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18915388 | Ccnl1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN regulation of mRNA splicing, via spliceosome (ortholog); regulation of RNA splicing (ortholog); FOUND IN cyclin L-CDK11 complex (ortholog); nuclear body (ortholog); nuclear spe ck (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 19259590 | CCNL1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of transcription by RNA polymerase II (inferred); FOUND IN nuclear speck (inferred); nucleoplasm (inferred); nucleus (inferre d) | | | | Dog | 6 | symbol | gene, protein-coding |
| 18769236 | CCNL1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN nuclear speck (ortholog) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155244442 | ccnl1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626157008 | Ccnl1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (ortholog); INVOLVED IN regulation of mRNA splicing, via spliceosome (ortholog); regulation of RNA splicing (ortholog); FOUND IN cyclin L-CDK11 complex (ortholog); nuclear body (ortholog); nuclear spe ck (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14202205 | CCNL1 | cyclin L1 | ENCODES a protein that exhibits cyclin-dependent protein serine/threonine kinase regulator activity (inferred); INVOLVED IN DNA-templated transcription (inferred); regulation of mRNA splicing, via spliceosome (inferred); regulation of RNA splicing (inferred); FOUND IN nuclear speck (ortholog) | | | | Pig | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155259341 | ccnl1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155244443 | ccnl1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1313689 | MCM2 | minichromosome maintenance complex component 2 | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012] | 3 | 127598411 | 127622436 | Human | 363 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |