| 1306912 | Kyat1 | kynurenine aminotransferase 1 | ENCODES a protein that exhibits cysteine-S-conjugate beta-lyase activity; glutamine-phenylpyruvate transaminase activity; kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN L-kynurenine catabolic process; pyruvate catabolic process; kynurenine metabolic process (ortholog); PARTICI PATES IN kynurenine metabolic pathway; selenoamino acid metabolic pathway; tryptophan metabolic pathway; ASSOCIATED WITH Experimental Arthritis; carcinoma (ortholog); Kidney Neoplasms (ortholog); FOUND IN cytosol; mitochondrion; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 3,3',5-triiodo-L-thyronine | 3 | 33857407 | 33891153 | Rat | 150 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1315794 | KYAT1 | kynurenine aminotransferase 1 | This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] | 9 | 128832942 | 128882523 | Human | 147 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1315795 | Kyat1 | kynurenine aminotransferase 1 | Predicted to enable cysteine-S-conjugate beta-lyase activity; protein homodimerization activity; and transaminase activity. Acts upstream of or within response to bacterium. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Is expressed in several structures, including ali mentary system; central nervous system; integumental system; respiratory system; and sensory organ. Orthologous to human KYAT1 (kynurenine aminotransferase 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 30075136 | 30096307 | Mouse | 163 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8828056 | Kyat1 | kynurenine aminotransferase 1 | ENCODES a protein that exhibits cysteine-S-conjugate beta-lyase activity (ortholog); glutamine-phenylpyruvate transaminase activity (ortholog); kynurenine-oxoglutarate transaminase activity (ortholog); INVOLVED IN kynurenine metabolic process (ortholog); L-kynurenine catabolic process (ortholog); py ruvate catabolic process (ortholog); PARTICIPATES IN kynurenine metabolic pathway; ASSOCIATED WITH carcinoma (ortholog); Experimental Arthritis (ortholog); Kidney Neoplasms (ortholog); FOUND IN cytosol (ortholog); mitochondrion (ortholog) | NW_004955570 | 1211950 | 1260561 | Chinchilla | 19 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18903064 | LOC101714047 | kynurenine--oxoglutarate transaminase 1 | ENCODES a protein that exhibits cysteine-S-conjugate beta-lyase activity (inferred); glutamine-phenylpyruvate transaminase activity (inferred); kynurenine-oxoglutarate transaminase activity (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); mitochondrion (inferred) | | | | Naked Mole-Rat | 12 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |