| 68382 | Cacnb1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits identical protein binding; phosphoprotein binding; protein domain specific binding; INVOLVED IN calcium ion transport (ortholog); cellular response to amyloid-beta (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathwa y; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse; postsynapse; voltage-gated calcium channel complex; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol | 10 | 83494509 | 83515164 | Rat | 213 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 68552 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activa tion and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008] | 17 | 39173453 | 39197669 | Human | 205 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 68553 | Cacnb1 | calcium channel, voltage-dependent, beta 1 subunit | Enables high voltage-gated calcium channel activity. Acts upstream of or within calcium ion transport and protein targeting to membrane. Located in T-tubule and sarcoplasmic reticulum. Part of voltage-gated calcium channel complex. Is active in presynapse. Is expressed in several structures, includi ng heart; lower leg rest of mesenchyme; nervous system; skeletal musculature; and urinary system. Orthologous to human CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 97892339 | 97913860 | Mouse | 222 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8803771 | Cacnb1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); cellular response to amyloid-beta (ortholog); protein targeting to membrane (orth olog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | NW_004955451 | 14041848 | 14059740 | Chinchilla | 109 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11853223 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway ; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | 17 | 18073818 | 18098400 | Bonobo | 117 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12126656 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits identical protein binding (ortholog); phosphoprotein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN calcium ion transport (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | 9 | 23182407 | 23197035 | Dog | 120 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12600878 | Cacnb1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway ; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | NW_004936490 | 14448305 | 14468785 | Squirrel | 117 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18702959 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway ; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | | | | Green Monkey | 116 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625879930 | Cacnb1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); cellular response to amyloid-beta (ortholog); protein targeting to membrane (orth olog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | | | | Black Rat | 109 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925490 | Cacnb1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits calcium channel regulator activity (ortholog); high voltage-gated calcium channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transport (ortholog); cellular response to amyloid-beta (ortholog); protein targeting to membrane (orth olog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | | | | Naked Mole-Rat | 116 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286081514 | cacnb1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 13977101 | CACNB1 | calcium voltage-gated channel auxiliary subunit beta 1 | ENCODES a protein that exhibits identical protein binding (ortholog); phosphoprotein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN calcium ion transport (ortholog); protein targeting to membrane (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog); presynapse (ortholog) | | | | Pig | 120 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 286081949 | cacnb1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329067 | cacnb1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38616926 | CACNB1-AS1 | CACNB1 antisense RNA 1 | | 17 | 39174629 | 39184373 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna, MODEL [RefSeq] |
| 16564187 | AC004408.1 | novel transcript, antisense to CACNB1 | | | | | Human | | name | gene, lncrna |
| 30306805 | JSRP1 | junctional sarcoplasmic reticulum protein 1 | The protein encoded by this gene is involved in excitation-contraction coupling at the sarcoplasmic reticulum. The encoded protein can interact with CACNA1S, CACNB1, and calsequestrin to help regulate calcium influx and efflux in skeletal muscle. [provided by Re fSeq, Jul 2012] | 19 | 2252252 | 2256417 | Human | 32 | description | gene, protein-coding, REVIEWED [RefSeq] |