| 621105 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); PARTICIPATES IN O-linked glycan biosynthetic pathway; ASSOCIATED WITH COV ID-19 (ortholog); FOUND IN membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl | 4 | 36894440 | 36932434 | Rat | 106 | symbol , old_gene_name , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 732029 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this g ene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010] | 7 | 7157377 | 7248616 | Human | 105 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 732030 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 | Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Acts upstream of or within angiogenesis; intestinal epithelial cell development; and protein O-linked glycosylation. Predicted to be located in membrane. Is expressed in several structures, including alimen tary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human C1GALT1 (core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 7845224 | 7872042 | Mouse | 190 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8864407 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (ortholog) | NW_004955432 | 14298873 | 14353824 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11827079 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); protein O-linked glycosylation (o rtholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred) | 7 | 7881615 | 8002349 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12366082 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); AS SOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred) | 14 | 22863861 | 22902232 | Dog | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12717876 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); protein O-linked glycosylation (o rtholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred) | NW_004936585 | 2650868 | 2682152 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14238482 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); AS SOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred) | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18538598 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (ortholog) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18900665 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); AS SOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20866946 | C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits glycosyltransferase activity (inferred); metal ion binding (inferred); N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN angiogenesis (inferred); kidney development (inferred); FOUND IN membrane (inferred) | | | | Green Monkey | 17 | symbol | gene, protein-coding |
| 155256829 | c1galt1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625969521 | C1galt1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN angiogenesis (ortholog); intestinal epithelial cell development (ortholog); kidney development (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN membrane (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155245798 | c1galt1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257521 | c1galt1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 285220507 | XB5871033 [provisional:c1galt1] | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 329332785 | XB5871033.L [provisional:c1galt1] | | | | | | African Clawed Frog | | symbol | gene, null |
| 329329935 | XB5871033.S [provisional:c1galt1] | | | | | | African Clawed Frog | | symbol | gene, null |
| 9850238 | C1GALT1P1 | C1GALT1 pseudogene 1 | INTERACTS WITH aristolochic acid A | 12 | 69284217 | 69285684 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 9850239 | C1GALT1P2 | C1GALT1 pseudogene 2 | | 5 | 56192368 | 56193835 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 10399653 | C1GALT1P3 | C1GALT1 pseudogene 3 | | 8 | 61909984 | 61910802 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1311230 | C1galt1c1 | C1GALT1-specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); PARTICIPATES IN O-linked glycan biosynthetic pathway; ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congenital disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-methoxyethanol | X | 122243736 | 122248217 | Rat | 107 | symbol , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1344219 | C1GALT1C1 | C1GALT1 specific chaperone 1 | This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Dec 2009] | X | 120625674 | 120630054 | Human | 147 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1620053 | C1galt1c1 | C1GALT1-specific chaperone 1 | Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Acts upstream of or within platelet activation; platelet morphogenesis; and protein O-linked glycosylation. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Tn polyagglutina tion syndrome and hemolytic-uremic syndrome. Orthologous to human C1GALT1C1 (C1GALT1 specific chaperone 1). [provided by Alliance of Genome Resources, Jul 2025] | X | 37719660 | 37724020 | Mouse | 117 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8737893 | C1galt1c1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog) | NW_004955572 | 1254289 | 1258561 | Chinchilla | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11981698 | C1GALT1C1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | X | 109905468 | 109909826 | Bonobo | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12136409 | C1GALT1C1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | X | 92581124 | 92584701 | Dog | 15 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12621523 | C1galt1c1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | NW_004936479 | 9416192 | 9420327 | Squirrel | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14281273 | C1GALT1C1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | | | | Pig | 15 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18731495 | C1GALT1C1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | | | | Green Monkey | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18913494 | C1galt1c1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog); FOUND IN membrane (inferred) | | | | Naked Mole-Rat | 16 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625849502 | C1galt1c1 | C1GALT1 specific chaperone 1 | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (ortholog); INVOLVED IN platelet activation (ortholog); platelet morphogenesis (ortholog); protein O-linked glycosylation (ortholog); ASSOCIATED WITH atypical hemolytic-uremic syndrome (ortholog); congeni tal disorder of glycosylation (ortholog); HEMOLYTIC UREMIC SYNDROME, ATYPICAL, 8, WITH RHIZOMELIC SHORT STATURE (ortholog) | | | | Black Rat | 14 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 8864402 | C1galt1c1l | C1GALT1 specific chaperone 1 like | | NW_004955441 | 10846009 | 10847263 | Chinchilla | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 9999358 | C1GALT1C1L | C1GALT1 specific chaperone 1 like | Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 2 | 43675151 | 43676429 | Human | 9 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 11942450 | C1GALT1C1L | C1GALT1 specific chaperone 1 like | | 2A | 43755825 | 43757186 | Bonobo | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12412947 | C1GALT1C1L | C1GALT1 specific chaperone 1 like | | 10 | 46139112 | 46139878 | Dog | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14187453 | C1GALT1C1L | C1GALT1 specific chaperone 1 like | | | | | Pig | | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18606887 | C1GALT1C1L | C1GALT1 specific chaperone 1 like | | | | | Green Monkey | | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18934025 | C1galt1c1l | C1GALT1 specific chaperone 1 like | ENCODES a protein that exhibits N-acetylgalactosaminide beta-1,3-galactosyltransferase activity (inferred); INVOLVED IN protein O-linked glycosylation (inferred); FOUND IN membrane (inferred) | | | | Naked Mole-Rat | 3 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14107320 | LOC100622121 | C1GALT1-specific chaperone 1-like | INVOLVED IN protein O-linked glycosylation (inferred); FOUND IN membrane (inferred) | | | | Pig | 2 | name | gene, protein-coding, MODEL [RefSeq] |
| 12578233 | LOC101978093 | C1GALT1-specific chaperone 1-like | | NW_004936498 | 3536915 | 3537871 | Squirrel | | name | gene, pseudo, MODEL [RefSeq] |
| 626101111 | LOC116912910 | C1GALT1-specific chaperone 1-like | | | | | Black Rat | | name | gene, protein-coding, MODEL [RefSeq] |
| 1563725 | C1galt1c1-ps1 | C1GALT1-specific chaperone 1, pseudogene 1 | INVOLVED IN protein O-linked glycosylation (inferred); FOUND IN membrane (inferred); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A | 14 | 55672375 | 55673587 | Rat | 4 | symbol , old_gene_name , PhenoGen , name | gene, pseudo, INFERRED [RefSeq] |
| 155235826 | c1galt1c1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155259820 | c1galt1c1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155246909 | c1galt1c1.S | | | | | | African Clawed Frog | | symbol | gene, null |