| 1557616 | Bmx | BMX non-receptor tyrosine kinase | Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in B cell receptor signaling pathway; adaptive immune response; and protein autophosphorylation. Predicted to be located in nucleoplasm and ruffle membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; hemolymphoid system; and mammary gland. Orthologous to human BMX (BMX non-receptor tyrosine kinase). [provided by Alliance of Genome Resources, Jul 2025] | X | 162975838 | 163041189 | Mouse | 68 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1565643 | Bmx | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN signal transduction (ortholog); FOUND IN plasma membrane (ortholog); ruffle membrane (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan | X | 33859128 | 33921876 | Rat | 67 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605440 | BMX | BMX non-receptor tyrosine kinase | This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] | X | 15500807 | 15556519 | Human | 74 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8955768 | Bmx | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN signal transduction (ortholog); FOUND IN plasma membrane (ortholog); ruffle membrane (ortholog) | NW_004955519 | 2638081 | 2689601 | Chinchilla | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11988462 | BMX | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); cell adhesion (inferred); intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (infe rred) | X | 8129158 | 8184910 | Bonobo | 30 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12353663 | BMX | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); cell adhesion (inferred); intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (infe rred) | X | 11742805 | 11795437 | Dog | 32 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12635419 | Bmx | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); cell adhesion (inferred); intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (infe rred) | NW_004936470 | 4914643 | 4962134 | Squirrel | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 13897714 | BMX | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); cell adhesion (inferred); intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (infe rred); INTERACTS WITH deoxynivalenol | | | | Pig | 34 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625853557 | Bmx | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN signal transduction (ortholog); FOUND IN plasma membrane (ortholog); ruffle membrane (ortholog) | | | | Black Rat | 10 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18908464 | Bmx | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN signal transduction (ortholog); FOUND IN plasma membrane (ortholog); ruffle membrane (ortholog) | | | | Naked Mole-Rat | 30 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18534105 | BMX | BMX non-receptor tyrosine kinase | ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); metal ion binding (inferred); INVOLVED IN apoptotic process (inferred); cell adhesion (inferred); intracellular signal transduction (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); plasma membrane (infe rred) | | | | Green Monkey | 30 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 734205 | PTPN21 | protein tyrosine phosphatase non-receptor type 21 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal d omain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008] | 14 | 88465778 | 88555007 | Human | 123 | description | gene, protein-coding, REVIEWED [RefSeq] |
