Bmp10 Gene Search Result

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14 records found for search term Bmp10

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1353352	BMP10	bone morphogenetic protein 10	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is ... (more) proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]	2	68860909	68871397	Human	112	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1558624	Bmp10	bone morphogenetic protein 10	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is ... (more) proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. Homozygous knockout mice for this gene exhibit impaired heart development and embryonic lethality. [provided by RefSeq, Aug 2016]	6	87405976	87411494	Mouse	162	symbol , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
1562986	Bmp10	bone morphogenetic protein 10	ENCODES a protein that exhibits growth factor activity (ortholog); hormone activity (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN positive regulation of cardiac muscle hypertrophy; sarcomere organization; activin receptor signaling pathway (ortholog); ASSOCIATED WITH L ... (more) eft Ventricular Hypertrophy; bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Fibrosis (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); extracellular space (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; aflatoxin B1	4	121423936	121439094	Rat	128	symbol , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
8922317	Bmp10	bone morphogenetic protein 10	ENCODES a protein that exhibits growth factor activity (ortholog); hormone activity (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN activin receptor signaling pathway (ortholog); adult heart development (ortholog); atrial cardiac muscle tissue morphogenesis (ortholog); A ... (more) SSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); extracellular space (ortholog)	NW_004955424	16124526	16130723	Chinchilla	46	symbol	gene, protein-coding, MODEL [RefSeq]
11694305	BMP10	bone morphogenetic protein 10	ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); hormone activity (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy comp ... (more) lex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)	2A	68901944	68912559	Bonobo	56	symbol	gene, protein-coding, MODEL [RefSeq]
12222922	BMP10	bone morphogenetic protein 10	ENCODES a protein that exhibits growth factor activity (inferred); hormone activity (inferred); receptor serine/threonine kinase binding (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias ... (more) -cloacal exstrophy complex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)	10	67717047	67724778	Dog	53	symbol	gene, protein-coding, MODEL [RefSeq]
12603299	Bmp10	bone morphogenetic protein 10	ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); hormone activity (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy comp ... (more) lex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)	NW_004936491	13180086	13186004	Squirrel	56	symbol	gene, protein-coding, MODEL [RefSeq]
14157316	BMP10	bone morphogenetic protein 10	ENCODES a protein that exhibits growth factor activity (inferred); hormone activity (inferred); receptor serine/threonine kinase binding (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias ... (more) -cloacal exstrophy complex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)				Pig	54	symbol	gene, protein-coding, MODEL [RefSeq]
625898599	Bmp10	bone morphogenetic protein 10	ENCODES a protein that exhibits growth factor activity (ortholog); hormone activity (ortholog); receptor serine/threonine kinase binding (ortholog); INVOLVED IN activin receptor signaling pathway (ortholog); adult heart development (ortholog); atrial cardiac muscle tissue morphogenesis (ortholog); A ... (more) SSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); extracellular space (ortholog)				Black Rat	46	symbol	gene, protein-coding, MODEL [RefSeq]
18906645	Bmp10	bone morphogenetic protein 10	ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); hormone activity (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy comp ... (more) lex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)				Naked Mole-Rat	56	symbol	gene, protein-coding, MODEL [RefSeq]
18510565	BMP10	bone morphogenetic protein 10	ENCODES a protein that exhibits cytokine activity (inferred); growth factor activity (inferred); hormone activity (inferred); INVOLVED IN BMP signaling pathway (ortholog); heart development (ortholog); kidney development (ortholog); ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy comp ... (more) lex (ortholog); Fibrosis (ortholog); Left Ventricular Hypertrophy (ortholog); FOUND IN cell surface (inferred); cytoplasm (inferred); extracellular region (inferred)				Green Monkey	56	symbol	gene, protein-coding, MODEL [RefSeq]
155235179	bmp10						Tropical Clawed Frog		symbol	gene, null
155235473	bmp10.L						African Clawed Frog		symbol	gene, null
155238340	bmp10.S						African Clawed Frog		symbol	gene, null