| 2194 | Bcan | brevican | ENCODES a protein that exhibits calcium ion binding (inferred); carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion; gliogenesis; neuron projection extension; ASSOCIATED WITH Brain Hypoxia-Ischemia; high grade glioma; middle cerebral artery infarctio n; FOUND IN axon; axon initial segment; cell surface; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 4,4'-sulfonyldiphenol | 2 | 175752333 | 175765766 | Rat | 131 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 10227 | Bcan | brevican | Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Involved in synapse maturation. Acts upstream of or within hippocampus development. Located in perineuronal net. Is active in glutamatergic synapse. Is expressed in several structur es, including brain; genitourinary system; lower jaw; sensory organ; and spinal cord. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human BCAN (brevican). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 87894839 | 87908458 | Mouse | 136 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 736888 | BCAN | brevican | This gene encodes a member of the lectican family of chondroitin sulfate proteoglycans that is specifically expressed in the central nervous system. This protein is developmentally regulated and may function in the formation of the brain extracellular matrix. This protein is highly expressed in glio mas and may promote the growth and cell motility of brain tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011] | 1 | 156642117 | 156659528 | Human | 127 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8836725 | Bcan | brevican | INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | NW_004955545 | 2723780 | 2739334 | Chinchilla | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11865890 | BCAN | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | 1 | 131985310 | 132003068 | Bonobo | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12122555 | BCAN | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Muscle Hypertonia; Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ort holog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | 7 | 41313578 | 41330178 | Dog | 41 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12483775 | Bcan | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | NW_004936580 | 5816196 | 5828531 | Squirrel | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925691 | Bcan | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | | | | Naked Mole-Rat | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626153776 | Bcan | brevican | INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | | | | Black Rat | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14218162 | BCAN | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | | | | Pig | 44 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285977665 | bcan | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18472462 | BCAN | brevican | ENCODES a protein that exhibits carbohydrate binding (inferred); hyaluronic acid binding (inferred); INVOLVED IN cell-matrix adhesion (ortholog); gliogenesis (ortholog); hippocampus development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Brain Hypoxia-Ischemia (ortholog); high grade glioma (ortholog); FOUND IN axon (ortholog); axon initial segment (ortholog); cell surface (ortholog) | | | | Green Monkey | 45 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288048690 | bcan.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 287905751 | bcan.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38651130 | BCAN-AS1 | BCAN antisense RNA 1 | | 1 | 156637782 | 156661409 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna |
| 153344617 | BCAN-AS2 | BCAN antisense RNA 2 | | 1 | 156645736 | 156661440 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16554574 | BCAN-AS2 | BCAN antisense RNA 2 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, lncrna |
| 16566380 | AL365181.3 | novel transcript, antisense to BCAN | | | | | Human | | name | gene, lncrna |